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SMILES: Cc1cn([C@@H]2O[C@H](CO[Si](C)(C)C(C)(C)C)[C@@H](O)[C@H]2O[Si](C)(C)C(C)(C)C)c(=O)n(CC(=O)OCc2ccccc2)c1=O

InChI Key: InChIKey=GJLXPBUYTOEBFF-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50403893   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Reverse transcriptase/RNaseH


(Human immunodeficiency virus 1)		BDBM50403893
PNG
(CHEMBL107000 | CHEMBL3142820)
Show SMILES Cc1cn([C@@H]2O[C@H](CO[Si](C)(C)C(C)(C)C)[C@@H](O)[C@H]2O[Si](C)(C)C(C)(C)C)c(=O)n(CC(=O)OCc2ccccc2)c1=O |r|
Show InChI InChI=1S/C31H50N2O8Si2/c1-21-17-33(29(37)32(27(21)36)18-24(34)38-19-22-15-13-12-14-16-22)28-26(41-43(10,11)31(5,6)7)25(35)23(40-28)20-39-42(8,9)30(2,3)4/h12-17,23,25-26,28,35H,18-20H2,1-11H3
PDB
MMDB

UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
n/an/an/an/a>1.00E+4n/an/an/an/a



Instituto de Química Médica (C.S.I.C.)

Curated by ChEMBL


Assay Description
Effective concentration required to inhibit HIV-1 induced cytopathicity by 50% in CEM cells

Bioorg Med Chem Lett 11: 3085-8 (2001)


BindingDB Entry DOI: 10.7270/Q2QC02S2
More data for this
Ligand-Target Pair