BDBM50404004 CHEMBL111224
SMILES: C[C@H]1CCC[C@H](\C=C\[C@H]2[C@H]3COC(=O)[C@H]3C[C@H]3CCCC[C@H]23)N1C
InChI Key: InChIKey=MYEVCMOLMLFGOC-QQZNOUBOSA-N
Data: 4 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Muscarinic acetylcholine receptor M2 (RAT) | BDBM50404004 (CHEMBL111224) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 7.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kyorin Pharmaceutical Co. Ltd. Curated by ChEMBL | Assay Description The compound was tested in vitro for binding activity against M2 muscarinic receptor in homogenates of the brainstem of rat using [3H]quinuclidinyl b... | Bioorg Med Chem Lett 12: 3271-3 (2002) BindingDB Entry DOI: 10.7270/Q2FT8N6H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Muscarinic acetylcholine receptor M1 (RAT) | BDBM50404004 (CHEMBL111224) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kyorin Pharmaceutical Co. Ltd. Curated by ChEMBL | Assay Description The compound was tested in vitro for binding activity against M1 muscarinic receptor in homogenates of the cerebral cortex of rat using [3H]pirenzepi... | Bioorg Med Chem Lett 12: 3271-3 (2002) BindingDB Entry DOI: 10.7270/Q2FT8N6H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Muscarinic acetylcholine receptor M2 (RAT) | BDBM50404004 (CHEMBL111224) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 794 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kyorin Pharmaceutical Co. Ltd. Curated by ChEMBL | Assay Description The compound was tested in vitro for binding activity against M2 muscarinic receptor in homogenates of the brainstem of rat using [3H]quinuclidinyl b... | Bioorg Med Chem Lett 12: 3271-3 (2002) BindingDB Entry DOI: 10.7270/Q2FT8N6H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Muscarinic acetylcholine receptor M1 (RAT) | BDBM50404004 (CHEMBL111224) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kyorin Pharmaceutical Co. Ltd. Curated by ChEMBL | Assay Description The compound was tested in vitro for binding activity against M1 muscarinic receptor in homogenates of the cerebral cortex of rat using [3H]pirenzepi... | Bioorg Med Chem Lett 12: 3271-3 (2002) BindingDB Entry DOI: 10.7270/Q2FT8N6H | |||||||||||
More data for this Ligand-Target Pair |