BDBM50404046 CHEMBL2111666

SMILES: COc1cc2ncc(O[C@@H]3CC4CCC3C4)nc2cc1OC

InChI Key: InChIKey=JXHVPOHWUDYYJU-QIMFLAQGSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50404046   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
PDGFR-beta/Platelet-derived growth factor receptor alpha (Homo sapiens (Human))	BDBM50404046 (CHEMBL2111666) Show SMILES COc1cc2ncc(O[C@@H]3CC4CCC3C4)nc2cc1OC |r,THB:8:9:15:13.12| Show InChI InChI=1S/C17H20N2O3/c1-20-15-7-12-13(8-16(15)21-2)19-17(9-18-12)22-14-6-10-3-4-11(14)5-10/h7-11,14H,3-6H2,1-2H3/t10?,11?,14-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	265	n/a	n/a	n/a	n/a	n/a	n/a
Aventis Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of Platelet-derived growth factor receptor				Bioorg Med Chem Lett 13: 3091-5 (2003) BindingDB Entry DOI: 10.7270/Q2N8796B
					More data for this Ligand-Target Pair