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SMILES: Cc1nc[nH]c1CSCCNC(NCCCc1cnc[nH]1)=NC#N

InChI Key: InChIKey=PQUQRZNCELUSMN-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50405174   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Histamine H2 receptor


(Cavia porcellus (domestic guinea pig))		BDBM50405174
PNG
(CHEMBL30761)
Show SMILES Cc1nc[nH]c1CSCCNC(NCCCc1cnc[nH]1)=NC#N |w:21.23|
Show InChI InChI=1S/C15H22N8S/c1-12-14(23-11-21-12)8-24-6-5-19-15(20-9-16)18-4-2-3-13-7-17-10-22-13/h7,10-11H,2-6,8H2,1H3,(H,17,22)(H,21,23)(H2,18,19,20)
UniProtKB/SwissProt

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CHEMBL
PC cid
PC sid
UniChem
PubMed
n/an/an/a 575n/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Antagonistic activity against H2 receptor in guinea pig.

J Med Chem 28: 1414-22 (1985)


BindingDB Entry DOI: 10.7270/Q2P27096
More data for this
Ligand-Target Pair