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BDBM50406655 CHEMBL432167

SMILES: O=C(NCCCOc1cccc(CN2CCCCC2)c1)NC1CC1

InChI Key: InChIKey=YAWMZMAKYMOTSW-UHFFFAOYSA-N

Data: 1 Kd

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50406655   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Histamine H2 receptor


(Cavia porcellus (domestic guinea pig))		BDBM50406655
PNG
(CHEMBL432167)
Show SMILES O=C(NCCCOc1cccc(CN2CCCCC2)c1)NC1CC1
Show InChI InChI=1S/C19H29N3O2/c23-19(21-17-8-9-17)20-10-5-13-24-18-7-4-6-16(14-18)15-22-11-2-1-3-12-22/h4,6-7,14,17H,1-3,5,8-13,15H2,(H2,20,21,23)
UniProtKB/SwissProt

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CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
n/an/an/a 47.9n/an/an/an/an/a



Kyorin Pharmaceutical Company, Ltd.

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against histamine H2-receptor in isolated Guinea pig right atria.

J Med Chem 35: 2446-51 (1992)


BindingDB Entry DOI: 10.7270/Q2V9898T
More data for this
Ligand-Target Pair