BDBM50406663 CHEMBL80069

SMILES: FC(F)(F)c1cccc(NC(=O)NCCCOc2cccc(CN3CCCCC3)c2)c1

InChI Key: InChIKey=UEYLTDPPLIJKCQ-UHFFFAOYSA-N

Data: 1 Kd

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50406663   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H2 receptor (Cavia porcellus (domestic guinea pig))	BDBM50406663 (CHEMBL80069) Show SMILES FC(F)(F)c1cccc(NC(=O)NCCCOc2cccc(CN3CCCCC3)c2)c1 Show InChI InChI=1S/C23H28F3N3O2/c24-23(25,26)19-8-5-9-20(16-19)28-22(30)27-11-6-14-31-21-10-4-7-18(15-21)17-29-12-2-1-3-13-29/h4-5,7-10,15-16H,1-3,6,11-14,17H2,(H2,27,28,30)	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	813	n/a	n/a	n/a	n/a	n/a
Kyorin Pharmaceutical Company, Ltd. Curated by ChEMBL					Assay Description In vitro inhibitory activity against histamine H2-receptor in isolated Guinea pig right atria.				J Med Chem 35: 2446-51 (1992) BindingDB Entry DOI: 10.7270/Q2V9898T
					More data for this Ligand-Target Pair