BDBM50406666 CHEMBL80046

SMILES: O=C(NCCCOc1cccc(CN2CCCCC2)c1)Nc1ccccc1

InChI Key: InChIKey=CQXOQBCTEPZRNB-UHFFFAOYSA-N

Data: 1 Kd

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50406666   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H2 receptor (Cavia porcellus (domestic guinea pig))	BDBM50406666 (CHEMBL80046) Show SMILES O=C(NCCCOc1cccc(CN2CCCCC2)c1)Nc1ccccc1 Show InChI InChI=1S/C22H29N3O2/c26-22(24-20-10-3-1-4-11-20)23-13-8-16-27-21-12-7-9-19(17-21)18-25-14-5-2-6-15-25/h1,3-4,7,9-12,17H,2,5-6,8,13-16,18H2,(H2,23,24,26)	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	126	n/a	n/a	n/a	n/a	n/a
Kyorin Pharmaceutical Company, Ltd. Curated by ChEMBL					Assay Description In vitro inhibitory activity against histamine H2-receptor in isolated Guinea pig right atria.				J Med Chem 35: 2446-51 (1992) BindingDB Entry DOI: 10.7270/Q2V9898T
					More data for this Ligand-Target Pair