BDBM50407399 CHEMBL315223

SMILES: Cn1ccc2c3CCN(C(=O)Nc4cccnc4)c3ccc12

InChI Key: InChIKey=WWORPZXUCHHSOT-UHFFFAOYSA-N

Data: 1 KI  2 Kd

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50407399   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serotonin receptor 2a and 2c (5HT2A and 5HT2C) (Rattus norvegicus (Rat))	BDBM50407399 (CHEMBL315223) Show SMILES Cn1ccc2c3CCN(C(=O)Nc4cccnc4)c3ccc12 Show InChI InChI=1S/C17H16N4O/c1-20-9-6-13-14-7-10-21(16(14)5-4-15(13)20)17(22)19-12-3-2-8-18-11-12/h2-6,8-9,11H,7,10H2,1H3,(H,19,22)	KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	25.1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals Curated by ChEMBL					Assay Description Displacement of [3H]mesulergine from rat 5-HT2C receptor expressed in HEK293				J Med Chem 39: 4966-77 (1997) Article DOI: 10.1021/jm960571v BindingDB Entry DOI: 10.7270/Q2S75HJF
					More data for this Ligand-Target Pair
Serotonin receptor 2a and 2b (5HT2A and 5HT2B) (RAT)	BDBM50407399 (CHEMBL315223) Show SMILES Cn1ccc2c3CCN(C(=O)Nc4cccnc4)c3ccc12 Show InChI InChI=1S/C17H16N4O/c1-20-9-6-13-14-7-10-21(16(14)5-4-15(13)20)17(22)19-12-3-2-8-18-11-12/h2-6,8-9,11H,7,10H2,1H3,(H,19,22)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	17.8	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals Curated by ChEMBL					Assay Description Inhibitory potency against rat stomach fundus 5-hydroxytryptamine 2B receptor				J Med Chem 38: 2524-30 (1995) BindingDB Entry DOI: 10.7270/Q2MP54HC
					More data for this Ligand-Target Pair
Serotonin receptor 2a and 2b (5HT2A and 5HT2B) (RAT)	BDBM50407399 (CHEMBL315223) Show SMILES Cn1ccc2c3CCN(C(=O)Nc4cccnc4)c3ccc12 Show InChI InChI=1S/C17H16N4O/c1-20-9-6-13-14-7-10-21(16(14)5-4-15(13)20)17(22)19-12-3-2-8-18-11-12/h2-6,8-9,11H,7,10H2,1H3,(H,19,22)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	15.8	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of 5-HT binding to 5-HT2B receptor of Rat stomach fundus				J Med Chem 39: 4966-77 (1997) Article DOI: 10.1021/jm960571v BindingDB Entry DOI: 10.7270/Q2S75HJF
					More data for this Ligand-Target Pair