null

SMILES: CN1Cc2ccccc2[C@H](N=C1CCc1ccc(NS(C)(=O)=O)cc1)c1ccc(F)cc1F

InChI Key: InChIKey=DZEIWSBKZLSWGF-VWLOTQADSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50407404   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium channel protein type 5 subunit alpha (Homo sapiens (Human))	BDBM50407404 (CHEMBL2092890) Show SMILES CN1Cc2ccccc2[C@H](N=C1CCc1ccc(NS(C)(=O)=O)cc1)c1ccc(F)cc1F |r,c:11| Show InChI InChI=1S/C25H25F2N3O2S/c1-30-16-18-5-3-4-6-21(18)25(22-13-10-19(26)15-23(22)27)28-24(30)14-9-17-7-11-20(12-8-17)29-33(2,31)32/h3-8,10-13,15,25,29H,9,14,16H2,1-2H3/t25-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Sterling Winthrop Research Curated by ChEMBL					Assay Description Blockade of Na+ current in frog oocytes expressing human cardiac sodium channel (HH1)				J Med Chem 38: 2551-6 (1995) BindingDB Entry DOI: 10.7270/Q2H132N3
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50407404 (CHEMBL2092890) Show SMILES CN1Cc2ccccc2[C@H](N=C1CCc1ccc(NS(C)(=O)=O)cc1)c1ccc(F)cc1F |r,c:11| Show InChI InChI=1S/C25H25F2N3O2S/c1-30-16-18-5-3-4-6-21(18)25(22-13-10-19(26)15-23(22)27)28-24(30)14-9-17-7-11-20(12-8-17)29-33(2,31)32/h3-8,10-13,15,25,29H,9,14,16H2,1-2H3/t25-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
Sterling Winthrop Research Curated by ChEMBL					Assay Description Blockade of the delayed rectifier K+ current (IKr) of guinea pig myocytes				J Med Chem 38: 2551-6 (1995) BindingDB Entry DOI: 10.7270/Q2H132N3
					More data for this Ligand-Target Pair