BDBM50407743 CHEMBL2114381

SMILES: CCN1c2cc(C)c(C)nc2N(C)C(=O)c2cc(N)cnc12

InChI Key: InChIKey=VWHLPLLRIGGLRG-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50407743   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50407743 (CHEMBL2114381) Show SMILES CCN1c2cc(C)c(C)nc2N(C)C(=O)c2cc(N)cnc12 Show InChI InChI=1S/C16H19N5O/c1-5-21-13-6-9(2)10(3)19-15(13)20(4)16(22)12-7-11(17)8-18-14(12)21/h6-8H,5,17H2,1-4H3	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Curated by ChEMBL					Assay Description In vitro for inhibition of HIV-1 reverse transcriptase.				J Med Chem 38: 1406-10 (1995) BindingDB Entry DOI: 10.7270/Q2MG7NJQ
					More data for this Ligand-Target Pair