Found 12 hits for monomerid = 50407789 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Serotonin 3a (5-HT3a)/3b (5-HT3b) receptor
(Rattus norvegicus-RAT) | BDBM50407789
(CHEMBL52772)Show InChI InChI=1S/C20H19FN4S/c21-16-5-3-15(4-6-16)14-23-9-11-24(12-10-23)19-17-2-1-8-25(17)18-7-13-26-20(18)22-19/h1-8,13H,9-12,14H2 | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.20 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Caen
Curated by ChEMBL
| Assay Description Binding affinity towards 5-hydroxytryptamine 3 receptor |
J Med Chem 39: 2068-80 (1996)
Article DOI: 10.1021/jm950543x BindingDB Entry DOI: 10.7270/Q2T72JNC |
More data for this Ligand-Target Pair | |
Serotonin 3a (5-HT3a)/3b (5-HT3b)/3c (5-HT3c)/3d (5-HT3d)/3e (5-HT3e) receptor
(Homo sapiens (Human)) | BDBM50407789
(CHEMBL52772)Show InChI InChI=1S/C20H19FN4S/c21-16-5-3-15(4-6-16)14-23-9-11-24(12-10-23)19-17-2-1-8-25(17)18-7-13-26-20(18)22-19/h1-8,13H,9-12,14H2 | PDB MMDB
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.20 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Caen
Curated by ChEMBL
| Assay Description Binding affinity against 5-hydroxytryptamine 3 receptor was measured using [3H]granisetron as radioligand |
J Med Chem 40: 1808-19 (1997)
Article DOI: 10.1021/jm960501o BindingDB Entry DOI: 10.7270/Q20R9QMC |
More data for this Ligand-Target Pair | |
Serotonin 1B/1D receptor
(Rattus norvegicus (Rat)) | BDBM50407789
(CHEMBL52772)Show InChI InChI=1S/C20H19FN4S/c21-16-5-3-15(4-6-16)14-23-9-11-24(12-10-23)19-17-2-1-8-25(17)18-7-13-26-20(18)22-19/h1-8,13H,9-12,14H2 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.58E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Caen
Curated by ChEMBL
| Assay Description Binding affinity for 5-hydroxytryptamine 1B receptor |
J Med Chem 39: 2068-80 (1996)
Article DOI: 10.1021/jm950543x BindingDB Entry DOI: 10.7270/Q2T72JNC |
More data for this Ligand-Target Pair | |
Serotonin 1d (5-HT1d) receptor
(Sus scrofa) | BDBM50407789
(CHEMBL52772)Show InChI InChI=1S/C20H19FN4S/c21-16-5-3-15(4-6-16)14-23-9-11-24(12-10-23)19-17-2-1-8-25(17)18-7-13-26-20(18)22-19/h1-8,13H,9-12,14H2 | UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Caen
Curated by ChEMBL
| Assay Description Binding affinity for 5-hydroxytryptamine 1D receptor |
J Med Chem 39: 2068-80 (1996)
Article DOI: 10.1021/jm950543x BindingDB Entry DOI: 10.7270/Q2T72JNC |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 2C
(Homo sapiens (Human)) | BDBM50407789
(CHEMBL52772)Show InChI InChI=1S/C20H19FN4S/c21-16-5-3-15(4-6-16)14-23-9-11-24(12-10-23)19-17-2-1-8-25(17)18-7-13-26-20(18)22-19/h1-8,13H,9-12,14H2 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.38E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Caen
Curated by ChEMBL
| Assay Description Binding affinity towards 5-hydroxytryptamine 2C receptor |
J Med Chem 39: 2068-80 (1996)
Article DOI: 10.1021/jm950543x BindingDB Entry DOI: 10.7270/Q2T72JNC |
More data for this Ligand-Target Pair | |
Serotonin 1B/1D receptor
(Rattus norvegicus (Rat)) | BDBM50407789
(CHEMBL52772)Show InChI InChI=1S/C20H19FN4S/c21-16-5-3-15(4-6-16)14-23-9-11-24(12-10-23)19-17-2-1-8-25(17)18-7-13-26-20(18)22-19/h1-8,13H,9-12,14H2 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Caen
Curated by ChEMBL
| Assay Description Binding affinity towards 5-hydroxytryptamine 1B receptor was measured using [3H]5-HT as radioligand |
J Med Chem 40: 1808-19 (1997)
Article DOI: 10.1021/jm960501o BindingDB Entry DOI: 10.7270/Q20R9QMC |
More data for this Ligand-Target Pair | |
Serotonin 2a (5-HT2a) receptor
(BOVINE) | BDBM50407789
(CHEMBL52772)Show InChI InChI=1S/C20H19FN4S/c21-16-5-3-15(4-6-16)14-23-9-11-24(12-10-23)19-17-2-1-8-25(17)18-7-13-26-20(18)22-19/h1-8,13H,9-12,14H2 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 3.80E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Caen
Curated by ChEMBL
| Assay Description Binding affinity towards 5-hydroxytryptamine 2A receptor |
J Med Chem 39: 2068-80 (1996)
Article DOI: 10.1021/jm950543x BindingDB Entry DOI: 10.7270/Q2T72JNC |
More data for this Ligand-Target Pair | |
Serotonin 1d (5-HT1d) receptor
(Sus scrofa) | BDBM50407789
(CHEMBL52772)Show InChI InChI=1S/C20H19FN4S/c21-16-5-3-15(4-6-16)14-23-9-11-24(12-10-23)19-17-2-1-8-25(17)18-7-13-26-20(18)22-19/h1-8,13H,9-12,14H2 | UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Caen
Curated by ChEMBL
| Assay Description Binding affinity against 5-hydroxytryptamine 1D receptor was measured using [3H]5-HT as radioligand |
J Med Chem 40: 1808-19 (1997)
Article DOI: 10.1021/jm960501o BindingDB Entry DOI: 10.7270/Q20R9QMC |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 1A
(Homo sapiens (Human)) | BDBM50407789
(CHEMBL52772)Show InChI InChI=1S/C20H19FN4S/c21-16-5-3-15(4-6-16)14-23-9-11-24(12-10-23)19-17-2-1-8-25(17)18-7-13-26-20(18)22-19/h1-8,13H,9-12,14H2 | PDB
UniProtKB/SwissProt UniProtKB/TrEMBL
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.45E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Caen
Curated by ChEMBL
| Assay Description Binding affinity against 5-hydroxytryptamine 1A receptor was measured using [3H]8-OH-DPAT as radioligand |
J Med Chem 40: 1808-19 (1997)
Article DOI: 10.1021/jm960501o BindingDB Entry DOI: 10.7270/Q20R9QMC |
More data for this Ligand-Target Pair | |
Serotonin 2a (5-HT2a) receptor
(BOVINE) | BDBM50407789
(CHEMBL52772)Show InChI InChI=1S/C20H19FN4S/c21-16-5-3-15(4-6-16)14-23-9-11-24(12-10-23)19-17-2-1-8-25(17)18-7-13-26-20(18)22-19/h1-8,13H,9-12,14H2 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 3.80E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Caen
Curated by ChEMBL
| Assay Description Binding affinity against 5-hydroxytryptamine 2A receptor was measured using [3H]ketanserin as radioligand |
J Med Chem 40: 1808-19 (1997)
Article DOI: 10.1021/jm960501o BindingDB Entry DOI: 10.7270/Q20R9QMC |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 2C
(Homo sapiens (Human)) | BDBM50407789
(CHEMBL52772)Show InChI InChI=1S/C20H19FN4S/c21-16-5-3-15(4-6-16)14-23-9-11-24(12-10-23)19-17-2-1-8-25(17)18-7-13-26-20(18)22-19/h1-8,13H,9-12,14H2 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Caen
Curated by ChEMBL
| Assay Description Binding affinity against 5-Hydroxytryptamine 2C Receptor was measured using [3H]N-methyl-mesulergine as radioligand |
J Med Chem 40: 1808-19 (1997)
Article DOI: 10.1021/jm960501o BindingDB Entry DOI: 10.7270/Q20R9QMC |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 1A
(Homo sapiens (Human)) | BDBM50407789
(CHEMBL52772)Show InChI InChI=1S/C20H19FN4S/c21-16-5-3-15(4-6-16)14-23-9-11-24(12-10-23)19-17-2-1-8-25(17)18-7-13-26-20(18)22-19/h1-8,13H,9-12,14H2 | PDB
UniProtKB/SwissProt UniProtKB/TrEMBL
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.45E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Caen
Curated by ChEMBL
| Assay Description Binding affinity for 5-hydroxytryptamine 1A receptor |
J Med Chem 39: 2068-80 (1996)
Article DOI: 10.1021/jm950543x BindingDB Entry DOI: 10.7270/Q2T72JNC |
More data for this Ligand-Target Pair | |