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BDBM50408390 CHEMBL169229

SMILES: COc1c(cc(Br)c2ccccc12)C(=O)NCCN1CCN(CC1)c1cccc(Cl)c1C

InChI Key: InChIKey=SATOYXZJVAZVKU-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50408390   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
D(3) dopamine receptor


(Homo sapiens (Human))		BDBM50408390
PNG
(CHEMBL169229)
Show SMILES COc1c(cc(Br)c2ccccc12)C(=O)NCCN1CCN(CC1)c1cccc(Cl)c1C
Show InChI InChI=1S/C25H27BrClN3O2/c1-17-22(27)8-5-9-23(17)30-14-12-29(13-15-30)11-10-28-25(31)20-16-21(26)18-6-3-4-7-19(18)24(20)32-2/h3-9,16H,10-15H2,1-2H3,(H,28,31)
PDB

UniProtKB/SwissProt

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UniChem

Similars
Article
PubMed
 50.1n/an/an/an/an/an/an/an/a



University Centre for Pharmacy

Curated by ChEMBL


Assay Description
Competitive inhibition of [3H]spiperone binding to the human dopamine receptor D3 expressed in CHO cells, expressed as 10log Ki

J Med Chem 40: 833-40 (1997)


Article DOI: 10.1021/jm9605952
BindingDB Entry DOI: 10.7270/Q23J3F5T
More data for this
Ligand-Target Pair