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SMILES: COc1c(Cl)cc(Cl)c(O)c1C(=O)NCCN1CCN(CC1)c1cccc(Cl)c1Cl

InChI Key: InChIKey=MGAAQQVYULJSPC-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50408400   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
D(3) dopamine receptor


(Homo sapiens (Human))		BDBM50408400
PNG
(CHEMBL168245)
Show SMILES COc1c(Cl)cc(Cl)c(O)c1C(=O)NCCN1CCN(CC1)c1cccc(Cl)c1Cl
Show InChI InChI=1S/C20H21Cl4N3O3/c1-30-19-14(23)11-13(22)18(28)16(19)20(29)25-5-6-26-7-9-27(10-8-26)15-4-2-3-12(21)17(15)24/h2-4,11,28H,5-10H2,1H3,(H,25,29)
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Similars
Article
PubMed
 501n/an/an/an/an/an/an/an/a



University Centre for Pharmacy

Curated by ChEMBL


Assay Description
Competitive inhibition of [3H]spiperone binding to the human dopamine receptor D3 expressed in CHO cells, expressed as 10log Ki

J Med Chem 40: 833-40 (1997)


Article DOI: 10.1021/jm9605952
BindingDB Entry DOI: 10.7270/Q23J3F5T
More data for this
Ligand-Target Pair