BDBM50409200 CHEMBL412882

SMILES: Clc1ccc(CNC(=S)N2CCC(CC2)c2cnc[nH]2)cc1

InChI Key: InChIKey=XQWKLOMHNQDDHP-UHFFFAOYSA-N

Data: 2 Kd

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50409200   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
HRH3 (GUINEA PIG)	BDBM50409200 (CHEMBL412882) Show SMILES Clc1ccc(CNC(=S)N2CCC(CC2)c2cnc[nH]2)cc1 Show InChI InChI=1S/C16H19ClN4S/c17-14-3-1-12(2-4-14)9-19-16(22)21-7-5-13(6-8-21)15-10-18-11-20-15/h1-4,10-11,13H,5-9H2,(H,18,20)(H,19,22)	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	61.7	n/a	n/a	n/a	n/a	n/a
De Novo Pharmaceuticals Curated by ChEMBL					Assay Description Displacement of [3H]Nalpha-methylhistamine from histamine H3 receptors in homogenates of rat cerebral cortex				J Med Chem 44: 1666-74 (2001) BindingDB Entry DOI: 10.7270/Q2WH2QP8
					More data for this Ligand-Target Pair
HRH3 (GUINEA PIG)	BDBM50409200 (CHEMBL412882) Show SMILES Clc1ccc(CNC(=S)N2CCC(CC2)c2cnc[nH]2)cc1 Show InChI InChI=1S/C16H19ClN4S/c17-14-3-1-12(2-4-14)9-19-16(22)21-7-5-13(6-8-21)15-10-18-11-20-15/h1-4,10-11,13H,5-9H2,(H,18,20)(H,19,22)	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	61.7	n/a	n/a	n/a	n/a	n/a
Vrije Universiteit Curated by ChEMBL					Assay Description In vitro histamine H3 receptor antagonist activity was determined on guinea pig jejunum				J Med Chem 43: 1754-61 (2000) BindingDB Entry DOI: 10.7270/Q2GM88JP
					More data for this Ligand-Target Pair