null

SMILES: Cc1cn(C2OC(CO[Si](C)(C)C(C)(C)C)C3(OS(=O)(=O)C(Br)=C3N)C2O[Si](C)(C)C(C)(C)C)c(=O)[nH]c1=O

InChI Key: InChIKey=GJCJARHLMQOCIA-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50409558   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50409558 (CHEMBL339662) Show SMILES Cc1cn(C2OC(CO[Si](C)(C)C(C)(C)C)C3(OS(=O)(=O)C(Br)=C3N)C2O[Si](C)(C)C(C)(C)C)c(=O)[nH]c1=O |c:22| Show InChI InChI=1S/C24H42BrN3O8SSi2/c1-14-12-28(21(30)27-19(14)29)20-17(35-39(10,11)23(5,6)7)24(16(26)18(25)37(31,32)36-24)15(34-20)13-33-38(8,9)22(2,3)4/h12,15,17,20H,13,26H2,1-11H3,(H,27,29,30)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	850	n/a	n/a	n/a	n/a
Instituto de Qu£mica M£dica (C.S.I.C.) Curated by ChEMBL					Assay Description Effective concentration required to inhibit HIV-1 induced cytopathicity in CEM cell culture by 50%.				J Med Chem 45: 3934-45 (2002) BindingDB Entry DOI: 10.7270/Q2639QXQ
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50409558 (CHEMBL339662) Show SMILES Cc1cn(C2OC(CO[Si](C)(C)C(C)(C)C)C3(OS(=O)(=O)C(Br)=C3N)C2O[Si](C)(C)C(C)(C)C)c(=O)[nH]c1=O |c:22| Show InChI InChI=1S/C24H42BrN3O8SSi2/c1-14-12-28(21(30)27-19(14)29)20-17(35-39(10,11)23(5,6)7)24(16(26)18(25)37(31,32)36-24)15(34-20)13-33-38(8,9)22(2,3)4/h12,15,17,20H,13,26H2,1-11H3,(H,27,29,30)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	930	n/a	n/a	n/a	n/a
Instituto de Qu£mica M£dica (C.S.I.C.) Curated by ChEMBL					Assay Description Effective concentration required to inhibit HIV-1 induced cytopathicity in MT-4 cell culture by 50%.				J Med Chem 45: 3934-45 (2002) BindingDB Entry DOI: 10.7270/Q2639QXQ
					More data for this Ligand-Target Pair