null

SMILES: Cc1cn(C2OC(CO[Si](C)(C)C(C)(C)C)C3(OS(=O)(=O)C(CC(N)=O)=C3NCC(N)=O)C2O[Si](C)(C)C(C)(C)C)c(=O)n(C)c1=O

InChI Key: InChIKey=OYDLSDANBNZGBF-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50409561   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50409561 (CHEMBL265105) Show SMILES Cc1cn(C2OC(CO[Si](C)(C)C(C)(C)C)C3(OS(=O)(=O)C(CC(N)=O)=C3NCC(N)=O)C2O[Si](C)(C)C(C)(C)C)c(=O)n(C)c1=O |c:25| Show InChI InChI=1S/C29H51N5O10SSi2/c1-17-15-34(26(38)33(8)24(17)37)25-23(43-47(11,12)28(5,6)7)29(19(42-25)16-41-46(9,10)27(2,3)4)22(32-14-21(31)36)18(13-20(30)35)45(39,40)44-29/h15,19,23,25,32H,13-14,16H2,1-12H3,(H2,30,35)(H2,31,36)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	>2.00E+3	n/a	n/a	n/a	n/a
Instituto de Qu£mica M£dica (C.S.I.C.) Curated by ChEMBL					Assay Description Effective concentration required to inhibit HIV-1 induced cytopathicity in CEM cell culture by 50%.				J Med Chem 45: 3934-45 (2002) BindingDB Entry DOI: 10.7270/Q2639QXQ
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50409561 (CHEMBL265105) Show SMILES Cc1cn(C2OC(CO[Si](C)(C)C(C)(C)C)C3(OS(=O)(=O)C(CC(N)=O)=C3NCC(N)=O)C2O[Si](C)(C)C(C)(C)C)c(=O)n(C)c1=O |c:25| Show InChI InChI=1S/C29H51N5O10SSi2/c1-17-15-34(26(38)33(8)24(17)37)25-23(43-47(11,12)28(5,6)7)29(19(42-25)16-41-46(9,10)27(2,3)4)22(32-14-21(31)36)18(13-20(30)35)45(39,40)44-29/h15,19,23,25,32H,13-14,16H2,1-12H3,(H2,30,35)(H2,31,36)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	>2.00E+3	n/a	n/a	n/a	n/a
Instituto de Qu£mica M£dica (C.S.I.C.) Curated by ChEMBL					Assay Description Effective concentration required to inhibit HIV-1 induced cytopathicity in MT-4 cell culture by 50%.				J Med Chem 45: 3934-45 (2002) BindingDB Entry DOI: 10.7270/Q2639QXQ
					More data for this Ligand-Target Pair