null

SMILES: Cc1cn(C2OC(CO[Si](C)(C)C(C)(C)C)C3(OS(=O)(=O)C(I)=C3N)C2O[Si](C)(C)C(C)(C)C)c(=O)n(C)c1=O

InChI Key: InChIKey=BIRHRYKGIRQHAT-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50409568   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50409568 (CHEMBL339262) Show SMILES Cc1cn(C2OC(CO[Si](C)(C)C(C)(C)C)C3(OS(=O)(=O)C(I)=C3N)C2O[Si](C)(C)C(C)(C)C)c(=O)n(C)c1=O |c:22| Show InChI InChI=1S/C25H44IN3O8SSi2/c1-15-13-29(22(31)28(8)20(15)30)21-18(36-40(11,12)24(5,6)7)25(17(27)19(26)38(32,33)37-25)16(35-21)14-34-39(9,10)23(2,3)4/h13,16,18,21H,14,27H2,1-12H3	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	50	n/a	n/a	n/a	n/a
Instituto de Qu£mica M£dica (C.S.I.C.) Curated by ChEMBL					Assay Description Effective concentration required to inhibit HIV-1 induced cytopathicity in CEM cell culture by 50%.				J Med Chem 45: 3934-45 (2002) BindingDB Entry DOI: 10.7270/Q2639QXQ
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50409568 (CHEMBL339262) Show SMILES Cc1cn(C2OC(CO[Si](C)(C)C(C)(C)C)C3(OS(=O)(=O)C(I)=C3N)C2O[Si](C)(C)C(C)(C)C)c(=O)n(C)c1=O |c:22| Show InChI InChI=1S/C25H44IN3O8SSi2/c1-15-13-29(22(31)28(8)20(15)30)21-18(36-40(11,12)24(5,6)7)25(17(27)19(26)38(32,33)37-25)16(35-21)14-34-39(9,10)23(2,3)4/h13,16,18,21H,14,27H2,1-12H3	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	110	n/a	n/a	n/a	n/a
Instituto de Qu£mica M£dica (C.S.I.C.) Curated by ChEMBL					Assay Description Effective concentration required to inhibit HIV-1 induced cytopathicity in MT-4 cell culture by 50%.				J Med Chem 45: 3934-45 (2002) BindingDB Entry DOI: 10.7270/Q2639QXQ
					More data for this Ligand-Target Pair