null

SMILES: COC(=O)CC=C1C(=N)C2(OS1(=O)=O)C(CO[Si](C)(C)C(C)(C)C)OC(C2O[Si](C)(C)C(C)(C)C)n1cc(C)c(=O)n(C)c1=O

InChI Key: InChIKey=PRCKGZMXGVFBQV-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50409573   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50409573 (CHEMBL340730) Show SMILES COC(=O)CC=C1C(=N)C2(OS1(=O)=O)C(CO[Si](C)(C)C(C)(C)C)OC(C2O[Si](C)(C)C(C)(C)C)n1cc(C)c(=O)n(C)c1=O |w:5.4| Show InChI InChI=1S/C29H49N3O10SSi2/c1-18-16-32(26(35)31(8)24(18)34)25-23(41-45(12,13)28(5,6)7)29(20(40-25)17-39-44(10,11)27(2,3)4)22(30)19(43(36,37)42-29)14-15-21(33)38-9/h14,16,20,23,25,30H,15,17H2,1-13H3	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	980	n/a	n/a	n/a	n/a
Instituto de Qu£mica M£dica (C.S.I.C.) Curated by ChEMBL					Assay Description Effective concentration required to inhibit HIV-1 induced cytopathicity in CEM cell culture by 50%.				J Med Chem 45: 3934-45 (2002) BindingDB Entry DOI: 10.7270/Q2639QXQ
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50409573 (CHEMBL340730) Show SMILES COC(=O)CC=C1C(=N)C2(OS1(=O)=O)C(CO[Si](C)(C)C(C)(C)C)OC(C2O[Si](C)(C)C(C)(C)C)n1cc(C)c(=O)n(C)c1=O |w:5.4| Show InChI InChI=1S/C29H49N3O10SSi2/c1-18-16-32(26(35)31(8)24(18)34)25-23(41-45(12,13)28(5,6)7)29(20(40-25)17-39-44(10,11)27(2,3)4)22(30)19(43(36,37)42-29)14-15-21(33)38-9/h14,16,20,23,25,30H,15,17H2,1-13H3	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	2.90E+3	n/a	n/a	n/a	n/a
Instituto de Qu£mica M£dica (C.S.I.C.) Curated by ChEMBL					Assay Description Effective concentration required to inhibit HIV-1 induced cytopathicity in MT-4 cell culture by 50%.				J Med Chem 45: 3934-45 (2002) BindingDB Entry DOI: 10.7270/Q2639QXQ
					More data for this Ligand-Target Pair