BDBM50409727 CHEMBL129411

SMILES: C(COc1ccc(CNC2CCCCC2)cc1)CN1CCCCC1

InChI Key: InChIKey=VMBGKHZBGBIRGK-UHFFFAOYSA-N

Data: 1 Kd

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50409727   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H3 receptor (Homo sapiens (Human))	BDBM50409727 (CHEMBL129411) Show SMILES C(COc1ccc(CNC2CCCCC2)cc1)CN1CCCCC1 Show InChI InChI=1S/C21H34N2O/c1-3-8-20(9-4-1)22-18-19-10-12-21(13-11-19)24-17-7-16-23-14-5-2-6-15-23/h10-13,20,22H,1-9,14-18H2	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	0.195	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL					Assay Description Histamine-induced inhibition of forskolin- stimulated cAMP accumulation in SK-N-MC cells overexpressing the human Histamine H3 receptor				J Med Chem 46: 3938-44 (2003) Article DOI: 10.1021/jm030185v BindingDB Entry DOI: 10.7270/Q2WQ051F
					More data for this Ligand-Target Pair