BDBM50409732 CHEMBL141238

SMILES: Cc1cc(C)c(NC(=O)C(=C\c2ccc(O)c(O)c2)\C#N)c(C)c1

InChI Key: InChIKey=ZOYSLPZNUAYMBX-OVCLIPMQSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50409732   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Receptor tyrosine-protein kinase erbB-2 (Homo sapiens (Human))	BDBM50409732 (CHEMBL141238) Show SMILES Cc1cc(C)c(NC(=O)C(=C\c2ccc(O)c(O)c2)\C#N)c(C)c1 Show InChI InChI=1S/C19H18N2O3/c1-11-6-12(2)18(13(3)7-11)21-19(24)15(10-20)8-14-4-5-16(22)17(23)9-14/h4-9,22-23H,1-3H3,(H,21,24)/b15-8+	PDB MMDB UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.09E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Tennessee Health Sciences Center Curated by ChEMBL					Assay Description Inhibitory activity tested against protein kinase HER-2				J Med Chem 46: 4657-68 (2003) Article DOI: 10.1021/jm030065n BindingDB Entry DOI: 10.7270/Q2N58NKR
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50409732 (CHEMBL141238) Show SMILES Cc1cc(C)c(NC(=O)C(=C\c2ccc(O)c(O)c2)\C#N)c(C)c1 Show InChI InChI=1S/C19H18N2O3/c1-11-6-12(2)18(13(3)7-11)21-19(24)15(10-20)8-14-4-5-16(22)17(23)9-14/h4-9,22-23H,1-3H3,(H,21,24)/b15-8+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.91E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Tennessee Health Sciences Center Curated by ChEMBL					Assay Description Inhibitory activity against epidermal growth factor receptor (EGFR)				J Med Chem 46: 4657-68 (2003) Article DOI: 10.1021/jm030065n BindingDB Entry DOI: 10.7270/Q2N58NKR
					More data for this Ligand-Target Pair