BDBM50409850 CHEMBL128376

SMILES: Cc1ccc(cc1)-n1cnnc1NS(=O)(=O)c1cc(C(=O)Nc2ccccc2)c(Cl)cc1S

InChI Key: InChIKey=PUVATWBAZBFXQP-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50409850   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Human immunodeficiency virus type 1 integrase (Human immunodeficiency virus 1)	BDBM50409850 (CHEMBL128376) Show SMILES Cc1ccc(cc1)-n1cnnc1NS(=O)(=O)c1cc(C(=O)Nc2ccccc2)c(Cl)cc1S Show InChI InChI=1S/C22H18ClN5O3S2/c1-14-7-9-16(10-8-14)28-13-24-26-22(28)27-33(30,31)20-11-17(18(23)12-19(20)32)21(29)25-15-5-3-2-4-6-15/h2-13,32H,1H3,(H,25,29)(H,26,27)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Southern California Curated by ChEMBL					Assay Description Inhibitory activity against DNA strand transfer by HIV integrase				J Med Chem 47: 385-99 (2004) Article DOI: 10.1021/jm030378i BindingDB Entry DOI: 10.7270/Q2M61MFX
					More data for this Ligand-Target Pair
Human immunodeficiency virus type 1 integrase (Human immunodeficiency virus 1)	BDBM50409850 (CHEMBL128376) Show SMILES Cc1ccc(cc1)-n1cnnc1NS(=O)(=O)c1cc(C(=O)Nc2ccccc2)c(Cl)cc1S Show InChI InChI=1S/C22H18ClN5O3S2/c1-14-7-9-16(10-8-14)28-13-24-26-22(28)27-33(30,31)20-11-17(18(23)12-19(20)32)21(29)25-15-5-3-2-4-6-15/h2-13,32H,1H3,(H,25,29)(H,26,27)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.03E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Southern California Curated by ChEMBL					Assay Description Inhibitory activity against 3' processing by HIV integrase				J Med Chem 47: 385-99 (2004) Article DOI: 10.1021/jm030378i BindingDB Entry DOI: 10.7270/Q2M61MFX
					More data for this Ligand-Target Pair