BDBM50410169 CHEMBL2021409

SMILES: COC(=O)C(Cc1ccccc1)NP([O-])(=O)OC[C@H]1O[C@H]([C@H](OC(C)C)[C@@H]1OC(C)C)n1cnc2c1nc(N)[nH]c2=O

InChI Key: InChIKey=DDTILYYEKMXGSN-RDNHWZOISA-M

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50410169   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Eukaryotic translation initiation factor 4E (eIF4E) (Homo sapiens (Human))	BDBM50410169 (CHEMBL2021409) Show SMILES COC(=O)C(Cc1ccccc1)NP([O-])(=O)OC[C@H]1O[C@H]([C@H](OC(C)C)[C@@H]1OC(C)C)n1cnc2c1nc(N)[nH]c2=O Show InChI InChI=1S/C26H37N6O9P/c1-14(2)39-20-18(12-38-42(35,36)31-17(25(34)37-5)11-16-9-7-6-8-10-16)41-24(21(20)40-15(3)4)32-13-28-19-22(32)29-26(27)30-23(19)33/h6-10,13-15,17-18,20-21,24H,11-12H2,1-5H3,(H2,31,35,36)(H3,27,29,30,33)/p-1/t17?,18-,20-,21-,24-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>4.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibitory concentration against 7-methyl-GTP binding to eukaryotic translation initiation factor 4E				Bioorg Med Chem Lett 15: 2177-80 (2005) Article DOI: 10.1016/j.bmcl.2005.01.080 BindingDB Entry DOI: 10.7270/Q27D2VWP
					More data for this Ligand-Target Pair