BDBM50410174 CHEMBL2079702

SMILES: CC(C)O[C@H]1[C@@H](COP([O-])=O)O[C@H](C1OC(C)C)n1c[n+](Cc2ccccc2)c2c1nc([NH-])[nH]c2=O

InChI Key: InChIKey=XUWAFIZZCNEPKH-GNIVAGDMSA-M

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50410174   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Eukaryotic translation initiation factor 4E (eIF4E) (Homo sapiens (Human))	BDBM50410174 (CHEMBL2079702) Show SMILES CC(C)O[C@H]1[C@@H](COP([O-])=O)O[C@H](C1OC(C)C)n1c[n+](Cc2ccccc2)c2c1nc([NH-])[nH]c2=O Show InChI InChI=1S/C23H32N5O7P/c1-13(2)33-18-16(11-32-36(30)31)35-22(19(18)34-14(3)4)28-12-27(10-15-8-6-5-7-9-15)17-20(28)25-23(24)26-21(17)29/h5-9,12-14,16,18-19,22,36H,10-11H2,1-4H3,(H3-,24,25,26,29,30,31)/p-1/t16-,18+,19?,22-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibitory concentration against 7-methyl-GTP binding to eukaryotic translation initiation factor 4E				Bioorg Med Chem Lett 15: 2177-80 (2005) Article DOI: 10.1016/j.bmcl.2005.01.080 BindingDB Entry DOI: 10.7270/Q27D2VWP
					More data for this Ligand-Target Pair