BDBM50410237 CHEMBL372237

SMILES: CCCC[C@H](NC(C)=O)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N(CCc1c[nH]c2ccccc12)CC(=O)NCC(N)=O

InChI Key: InChIKey=PNJHRYWDWYTSBM-MYOMABOUSA-N

Data: 3 IC50  3 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50410237   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM50410237 (CHEMBL372237) Show SMILES CCCC[C@H](NC(C)=O)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N(CCc1c[nH]c2ccccc12)CC(=O)NCC(N)=O Show InChI InChI=1S/C45H67N13O8/c1-3-4-16-34(54-29(2)59)41(63)53-27-39(61)55-35(18-10-11-21-46)42(64)57-37(24-30-13-6-5-7-14-30)43(65)56-36(19-12-22-50-45(48)49)44(66)58(28-40(62)52-26-38(47)60)23-20-31-25-51-33-17-9-8-15-32(31)33/h5-9,13-15,17,25,34-37,51H,3-4,10-12,16,18-24,26-28,46H2,1-2H3,(H2,47,60)(H,52,62)(H,53,63)(H,54,59)(H,55,61)(H,56,65)(H,57,64)(H4,48,49,50)/t34-,35-,36-,37+/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	316	n/a	n/a	n/a	n/a
Utrecht University Curated by ChEMBL					Assay Description Effective concentration against human melanocortin receptor-4 expressed in 293 HEK cells				J Med Chem 48: 4224-30 (2005) Article DOI: 10.1021/jm0490033 BindingDB Entry DOI: 10.7270/Q2QV3NQ5
					More data for this Ligand-Target Pair
Melanocortin receptor 5 (MC5R) (Mus musculus (Mouse))	BDBM50410237 (CHEMBL372237) Show SMILES CCCC[C@H](NC(C)=O)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N(CCc1c[nH]c2ccccc12)CC(=O)NCC(N)=O Show InChI InChI=1S/C45H67N13O8/c1-3-4-16-34(54-29(2)59)41(63)53-27-39(61)55-35(18-10-11-21-46)42(64)57-37(24-30-13-6-5-7-14-30)43(65)56-36(19-12-22-50-45(48)49)44(66)58(28-40(62)52-26-38(47)60)23-20-31-25-51-33-17-9-8-15-32(31)33/h5-9,13-15,17,25,34-37,51H,3-4,10-12,16,18-24,26-28,46H2,1-2H3,(H2,47,60)(H,52,62)(H,53,63)(H,54,59)(H,55,61)(H,56,65)(H,57,64)(H4,48,49,50)/t34-,35-,36-,37+/m0/s1	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Utrecht University Curated by ChEMBL					Assay Description Displacement of [125I]NDP-MSH from mouse melanocortin receptor-5 expressed in 293 HEK cells				J Med Chem 48: 4224-30 (2005) Article DOI: 10.1021/jm0490033 BindingDB Entry DOI: 10.7270/Q2QV3NQ5
					More data for this Ligand-Target Pair
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM50410237 (CHEMBL372237) Show SMILES CCCC[C@H](NC(C)=O)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N(CCc1c[nH]c2ccccc12)CC(=O)NCC(N)=O Show InChI InChI=1S/C45H67N13O8/c1-3-4-16-34(54-29(2)59)41(63)53-27-39(61)55-35(18-10-11-21-46)42(64)57-37(24-30-13-6-5-7-14-30)43(65)56-36(19-12-22-50-45(48)49)44(66)58(28-40(62)52-26-38(47)60)23-20-31-25-51-33-17-9-8-15-32(31)33/h5-9,13-15,17,25,34-37,51H,3-4,10-12,16,18-24,26-28,46H2,1-2H3,(H2,47,60)(H,52,62)(H,53,63)(H,54,59)(H,55,61)(H,56,65)(H,57,64)(H4,48,49,50)/t34-,35-,36-,37+/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	316	n/a	n/a	n/a	n/a	n/a	n/a
Utrecht University Curated by ChEMBL					Assay Description Displacement of [125I]NDP-MSH from human melanocortin receptor-4 expressed in 293 HEK cells				J Med Chem 48: 4224-30 (2005) Article DOI: 10.1021/jm0490033 BindingDB Entry DOI: 10.7270/Q2QV3NQ5
					More data for this Ligand-Target Pair
Melanocortin receptor 3 (Homo sapiens (Human))	BDBM50410237 (CHEMBL372237) Show SMILES CCCC[C@H](NC(C)=O)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N(CCc1c[nH]c2ccccc12)CC(=O)NCC(N)=O Show InChI InChI=1S/C45H67N13O8/c1-3-4-16-34(54-29(2)59)41(63)53-27-39(61)55-35(18-10-11-21-46)42(64)57-37(24-30-13-6-5-7-14-30)43(65)56-36(19-12-22-50-45(48)49)44(66)58(28-40(62)52-26-38(47)60)23-20-31-25-51-33-17-9-8-15-32(31)33/h5-9,13-15,17,25,34-37,51H,3-4,10-12,16,18-24,26-28,46H2,1-2H3,(H2,47,60)(H,52,62)(H,53,63)(H,54,59)(H,55,61)(H,56,65)(H,57,64)(H4,48,49,50)/t34-,35-,36-,37+/m0/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.94E+3	n/a	n/a	n/a	n/a	n/a	n/a
Utrecht University Curated by ChEMBL					Assay Description Effective concentration against human melanocortin receptor-3 expressed in 293 HEK cells				J Med Chem 48: 4224-30 (2005) Article DOI: 10.1021/jm0490033 BindingDB Entry DOI: 10.7270/Q2QV3NQ5
					More data for this Ligand-Target Pair
Melanocortin receptor 5 (MC5R) (Mus musculus (Mouse))	BDBM50410237 (CHEMBL372237) Show SMILES CCCC[C@H](NC(C)=O)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N(CCc1c[nH]c2ccccc12)CC(=O)NCC(N)=O Show InChI InChI=1S/C45H67N13O8/c1-3-4-16-34(54-29(2)59)41(63)53-27-39(61)55-35(18-10-11-21-46)42(64)57-37(24-30-13-6-5-7-14-30)43(65)56-36(19-12-22-50-45(48)49)44(66)58(28-40(62)52-26-38(47)60)23-20-31-25-51-33-17-9-8-15-32(31)33/h5-9,13-15,17,25,34-37,51H,3-4,10-12,16,18-24,26-28,46H2,1-2H3,(H2,47,60)(H,52,62)(H,53,63)(H,54,59)(H,55,61)(H,56,65)(H,57,64)(H4,48,49,50)/t34-,35-,36-,37+/m0/s1	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a
Utrecht University Curated by ChEMBL					Assay Description Effective concentration against mouse melanocortin receptor-5 expressed in 293 HEK cells				J Med Chem 48: 4224-30 (2005) Article DOI: 10.1021/jm0490033 BindingDB Entry DOI: 10.7270/Q2QV3NQ5
					More data for this Ligand-Target Pair
Melanocortin receptor 3 (Homo sapiens (Human))	BDBM50410237 (CHEMBL372237) Show SMILES CCCC[C@H](NC(C)=O)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N(CCc1c[nH]c2ccccc12)CC(=O)NCC(N)=O Show InChI InChI=1S/C45H67N13O8/c1-3-4-16-34(54-29(2)59)41(63)53-27-39(61)55-35(18-10-11-21-46)42(64)57-37(24-30-13-6-5-7-14-30)43(65)56-36(19-12-22-50-45(48)49)44(66)58(28-40(62)52-26-38(47)60)23-20-31-25-51-33-17-9-8-15-32(31)33/h5-9,13-15,17,25,34-37,51H,3-4,10-12,16,18-24,26-28,46H2,1-2H3,(H2,47,60)(H,52,62)(H,53,63)(H,54,59)(H,55,61)(H,56,65)(H,57,64)(H4,48,49,50)/t34-,35-,36-,37+/m0/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a
Utrecht University Curated by ChEMBL					Assay Description Effective concentration against human melanocortin receptor-3 expressed in 293 HEK cells				J Med Chem 48: 4224-30 (2005) Article DOI: 10.1021/jm0490033 BindingDB Entry DOI: 10.7270/Q2QV3NQ5
					More data for this Ligand-Target Pair