BDBM50410253 CHEMBL371610

SMILES: CCCCN(CC(=O)NCC(=O)N(CCCCN)CC(=O)N[C@H](Cc1ccccc1)C(=O)N(CCCNC(N)=N)CC(=O)N(CC(=O)NCC(N)=O)Cc1c[nH]c2ccccc12)C(C)=O

InChI Key: InChIKey=ZOTOEZBDEXRVQQ-PSXMRANNSA-N

Data: 2 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50410253   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM50410253 (CHEMBL371610) Show SMILES CCCCN(CC(=O)NCC(=O)N(CCCCN)CC(=O)N[C@H](Cc1ccccc1)C(=O)N(CCCNC(N)=N)CC(=O)N(CC(=O)NCC(N)=O)Cc1c[nH]c2ccccc12)C(C)=O Show InChI InChI=1S/C44H65N13O8/c1-3-4-19-54(31(2)58)27-38(60)52-25-41(63)55(20-11-10-17-45)29-40(62)53-36(22-32-13-6-5-7-14-32)43(65)56(21-12-18-49-44(47)48)30-42(64)57(28-39(61)51-24-37(46)59)26-33-23-50-35-16-9-8-15-34(33)35/h5-9,13-16,23,36,50H,3-4,10-12,17-22,24-30,45H2,1-2H3,(H2,46,59)(H,51,61)(H,52,60)(H,53,62)(H4,47,48,49)/t36-/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.98E+3	n/a	n/a	n/a	n/a	n/a	n/a
Utrecht University Curated by ChEMBL					Assay Description Displacement of [125I]NDP-MSH from human melanocortin receptor-4 expressed in 293 HEK cells				J Med Chem 48: 4224-30 (2005) Article DOI: 10.1021/jm0490033 BindingDB Entry DOI: 10.7270/Q2QV3NQ5
					More data for this Ligand-Target Pair
Melanocortin receptor 5 (MC5R) (Mus musculus (Mouse))	BDBM50410253 (CHEMBL371610) Show SMILES CCCCN(CC(=O)NCC(=O)N(CCCCN)CC(=O)N[C@H](Cc1ccccc1)C(=O)N(CCCNC(N)=N)CC(=O)N(CC(=O)NCC(N)=O)Cc1c[nH]c2ccccc12)C(C)=O Show InChI InChI=1S/C44H65N13O8/c1-3-4-19-54(31(2)58)27-38(60)52-25-41(63)55(20-11-10-17-45)29-40(62)53-36(22-32-13-6-5-7-14-32)43(65)56(21-12-18-49-44(47)48)30-42(64)57(28-39(61)51-24-37(46)59)26-33-23-50-35-16-9-8-15-34(33)35/h5-9,13-16,23,36,50H,3-4,10-12,17-22,24-30,45H2,1-2H3,(H2,46,59)(H,51,61)(H,52,60)(H,53,62)(H4,47,48,49)/t36-/m1/s1	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.98E+3	n/a	n/a	n/a	n/a	n/a	n/a
Utrecht University Curated by ChEMBL					Assay Description Displacement of [125I]NDP-MSH from mouse melanocortin receptor-5 expressed in 293 HEK cells				J Med Chem 48: 4224-30 (2005) Article DOI: 10.1021/jm0490033 BindingDB Entry DOI: 10.7270/Q2QV3NQ5
					More data for this Ligand-Target Pair
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM50410253 (CHEMBL371610) Show SMILES CCCCN(CC(=O)NCC(=O)N(CCCCN)CC(=O)N[C@H](Cc1ccccc1)C(=O)N(CCCNC(N)=N)CC(=O)N(CC(=O)NCC(N)=O)Cc1c[nH]c2ccccc12)C(C)=O Show InChI InChI=1S/C44H65N13O8/c1-3-4-19-54(31(2)58)27-38(60)52-25-41(63)55(20-11-10-17-45)29-40(62)53-36(22-32-13-6-5-7-14-32)43(65)56(21-12-18-49-44(47)48)30-42(64)57(28-39(61)51-24-37(46)59)26-33-23-50-35-16-9-8-15-34(33)35/h5-9,13-16,23,36,50H,3-4,10-12,17-22,24-30,45H2,1-2H3,(H2,46,59)(H,51,61)(H,52,60)(H,53,62)(H4,47,48,49)/t36-/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	5.01E+3	n/a	n/a	n/a	n/a
Utrecht University Curated by ChEMBL					Assay Description Displacement of [125I]NDP-MSH from human melanocortin receptor-4 expressed in 293 HEK cells				J Med Chem 48: 4224-30 (2005) Article DOI: 10.1021/jm0490033 BindingDB Entry DOI: 10.7270/Q2QV3NQ5
					More data for this Ligand-Target Pair