BDBM50410254 CHEMBL190203

SMILES: CCCCN(CC(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N(CC(=O)NCC(N)=O)Cc1c[nH]c2ccccc12)C(C)=O

InChI Key: InChIKey=YNLBTNFQOQDPOA-QGBCWPEESA-N

Data: 3 IC50  3 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50410254   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM50410254 (CHEMBL190203) Show SMILES CCCCN(CC(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N(CC(=O)NCC(N)=O)Cc1c[nH]c2ccccc12)C(C)=O Show InChI InChI=1S/C44H65N13O8/c1-3-4-21-56(29(2)58)27-39(61)52-25-38(60)53-34(17-10-11-19-45)41(63)55-36(22-30-13-6-5-7-14-30)42(64)54-35(18-12-20-49-44(47)48)43(65)57(28-40(62)51-24-37(46)59)26-31-23-50-33-16-9-8-15-32(31)33/h5-9,13-16,23,34-36,50H,3-4,10-12,17-22,24-28,45H2,1-2H3,(H2,46,59)(H,51,62)(H,52,61)(H,53,60)(H,54,64)(H,55,63)(H4,47,48,49)/t34-,35-,36+/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	631	n/a	n/a	n/a	n/a
Utrecht University Curated by ChEMBL					Assay Description Effective concentration against human melanocortin receptor-4 expressed in 293 HEK cells				J Med Chem 48: 4224-30 (2005) Article DOI: 10.1021/jm0490033 BindingDB Entry DOI: 10.7270/Q2QV3NQ5
					More data for this Ligand-Target Pair
Melanocortin receptor 5 (MC5R) (Mus musculus (Mouse))	BDBM50410254 (CHEMBL190203) Show SMILES CCCCN(CC(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N(CC(=O)NCC(N)=O)Cc1c[nH]c2ccccc12)C(C)=O Show InChI InChI=1S/C44H65N13O8/c1-3-4-21-56(29(2)58)27-39(61)52-25-38(60)53-34(17-10-11-19-45)41(63)55-36(22-30-13-6-5-7-14-30)42(64)54-35(18-12-20-49-44(47)48)43(65)57(28-40(62)51-24-37(46)59)26-31-23-50-33-16-9-8-15-32(31)33/h5-9,13-16,23,34-36,50H,3-4,10-12,17-22,24-28,45H2,1-2H3,(H2,46,59)(H,51,62)(H,52,61)(H,53,60)(H,54,64)(H,55,63)(H4,47,48,49)/t34-,35-,36+/m0/s1	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	3.98E+3	n/a	n/a	n/a	n/a
Utrecht University Curated by ChEMBL					Assay Description Effective concentration against mouse melanocortin receptor-5 expressed in 293 HEK cells				J Med Chem 48: 4224-30 (2005) Article DOI: 10.1021/jm0490033 BindingDB Entry DOI: 10.7270/Q2QV3NQ5
					More data for this Ligand-Target Pair
Melanocortin receptor 5 (MC5R) (Mus musculus (Mouse))	BDBM50410254 (CHEMBL190203) Show SMILES CCCCN(CC(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N(CC(=O)NCC(N)=O)Cc1c[nH]c2ccccc12)C(C)=O Show InChI InChI=1S/C44H65N13O8/c1-3-4-21-56(29(2)58)27-39(61)52-25-38(60)53-34(17-10-11-19-45)41(63)55-36(22-30-13-6-5-7-14-30)42(64)54-35(18-12-20-49-44(47)48)43(65)57(28-40(62)51-24-37(46)59)26-31-23-50-33-16-9-8-15-32(31)33/h5-9,13-16,23,34-36,50H,3-4,10-12,17-22,24-28,45H2,1-2H3,(H2,46,59)(H,51,62)(H,52,61)(H,53,60)(H,54,64)(H,55,63)(H4,47,48,49)/t34-,35-,36+/m0/s1	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.59E+3	n/a	n/a	n/a	n/a	n/a	n/a
Utrecht University Curated by ChEMBL					Assay Description Displacement of [125I]NDP-MSH from mouse melanocortin receptor-5 expressed in 293 HEK cells				J Med Chem 48: 4224-30 (2005) Article DOI: 10.1021/jm0490033 BindingDB Entry DOI: 10.7270/Q2QV3NQ5
					More data for this Ligand-Target Pair
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM50410254 (CHEMBL190203) Show SMILES CCCCN(CC(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N(CC(=O)NCC(N)=O)Cc1c[nH]c2ccccc12)C(C)=O Show InChI InChI=1S/C44H65N13O8/c1-3-4-21-56(29(2)58)27-39(61)52-25-38(60)53-34(17-10-11-19-45)41(63)55-36(22-30-13-6-5-7-14-30)42(64)54-35(18-12-20-49-44(47)48)43(65)57(28-40(62)51-24-37(46)59)26-31-23-50-33-16-9-8-15-32(31)33/h5-9,13-16,23,34-36,50H,3-4,10-12,17-22,24-28,45H2,1-2H3,(H2,46,59)(H,51,62)(H,52,61)(H,53,60)(H,54,64)(H,55,63)(H4,47,48,49)/t34-,35-,36+/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	794	n/a	n/a	n/a	n/a	n/a	n/a
Utrecht University Curated by ChEMBL					Assay Description Displacement of [125I]NDP-MSH from human melanocortin receptor-4 expressed in 293 HEK cells				J Med Chem 48: 4224-30 (2005) Article DOI: 10.1021/jm0490033 BindingDB Entry DOI: 10.7270/Q2QV3NQ5
					More data for this Ligand-Target Pair
Melanocortin receptor 3 (Homo sapiens (Human))	BDBM50410254 (CHEMBL190203) Show SMILES CCCCN(CC(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N(CC(=O)NCC(N)=O)Cc1c[nH]c2ccccc12)C(C)=O Show InChI InChI=1S/C44H65N13O8/c1-3-4-21-56(29(2)58)27-39(61)52-25-38(60)53-34(17-10-11-19-45)41(63)55-36(22-30-13-6-5-7-14-30)42(64)54-35(18-12-20-49-44(47)48)43(65)57(28-40(62)51-24-37(46)59)26-31-23-50-33-16-9-8-15-32(31)33/h5-9,13-16,23,34-36,50H,3-4,10-12,17-22,24-28,45H2,1-2H3,(H2,46,59)(H,51,62)(H,52,61)(H,53,60)(H,54,64)(H,55,63)(H4,47,48,49)/t34-,35-,36+/m0/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	794	n/a	n/a	n/a	n/a
Utrecht University Curated by ChEMBL					Assay Description Effective concentration against human melanocortin receptor-3 expressed in 293 HEK cells				J Med Chem 48: 4224-30 (2005) Article DOI: 10.1021/jm0490033 BindingDB Entry DOI: 10.7270/Q2QV3NQ5
					More data for this Ligand-Target Pair
Melanocortin receptor 3 (Homo sapiens (Human))	BDBM50410254 (CHEMBL190203) Show SMILES CCCCN(CC(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N(CC(=O)NCC(N)=O)Cc1c[nH]c2ccccc12)C(C)=O Show InChI InChI=1S/C44H65N13O8/c1-3-4-21-56(29(2)58)27-39(61)52-25-38(60)53-34(17-10-11-19-45)41(63)55-36(22-30-13-6-5-7-14-30)42(64)54-35(18-12-20-49-44(47)48)43(65)57(28-40(62)51-24-37(46)59)26-31-23-50-33-16-9-8-15-32(31)33/h5-9,13-16,23,34-36,50H,3-4,10-12,17-22,24-28,45H2,1-2H3,(H2,46,59)(H,51,62)(H,52,61)(H,53,60)(H,54,64)(H,55,63)(H4,47,48,49)/t34-,35-,36+/m0/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.26E+3	n/a	n/a	n/a	n/a	n/a	n/a
Utrecht University Curated by ChEMBL					Assay Description Displacement of [125I]NDP-MSH from human melanocortin receptor-3 expressed in 293 HEK cells				J Med Chem 48: 4224-30 (2005) Article DOI: 10.1021/jm0490033 BindingDB Entry DOI: 10.7270/Q2QV3NQ5
					More data for this Ligand-Target Pair