Found 3 hits for monomerid = 50410255 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kcal/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Melanocortin receptor 4
(Homo sapiens (Human)) | BDBM50410255
(CHEMBL2371828)Show SMILES CCCCN(CC(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N(CC(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCC(N)=O)Cc1ccccc1)C(C)=O |wU:37.37,13.13,26.26,(-9.04,-26.89,;-7.85,-25.9,;-6.41,-26.43,;-5.23,-25.45,;-3.78,-25.98,;-2.6,-24.99,;-1.15,-25.52,;-.89,-27.04,;.03,-24.54,;1.48,-25.07,;2.66,-24.08,;2.4,-22.56,;4.1,-24.61,;5.29,-23.62,;5.02,-22.11,;3.58,-21.58,;3.32,-20.06,;1.87,-19.53,;1.61,-18.01,;6.73,-24.16,;7,-25.67,;7.92,-23.17,;9.36,-23.7,;10.54,-22.71,;11.22,-21.33,;11.99,-23.25,;13.17,-22.26,;12.91,-20.74,;14.09,-19.76,;13.83,-18.24,;15.01,-17.25,;14.75,-15.73,;15.93,-14.75,;13.3,-15.2,;14.62,-22.79,;14.88,-24.31,;15.8,-21.8,;17.25,-22.34,;18.43,-21.35,;19.87,-21.88,;20.29,-23.36,;21.83,-23.42,;22.36,-21.97,;23.79,-21.4,;24.01,-19.88,;22.8,-18.93,;21.37,-19.5,;21.15,-21.02,;17.51,-23.85,;16.33,-24.84,;18.95,-24.38,;19.22,-25.9,;20.66,-26.43,;20.93,-27.95,;21.85,-25.45,;7.65,-21.65,;8.84,-20.67,;8.57,-19.15,;9.76,-18.16,;11.2,-18.69,;11.46,-20.21,;10.28,-21.2,;-3.52,-27.49,;-2.07,-28.03,;-4.7,-28.48,)| Show InChI InChI=1S/C44H65N13O8/c1-3-4-21-56(29(2)58)27-39(61)51-25-38(60)54-35(17-10-11-19-45)43(65)57(26-30-13-6-5-7-14-30)28-40(62)53-34(18-12-20-49-44(47)48)42(64)55-36(41(63)52-24-37(46)59)22-31-23-50-33-16-9-8-15-32(31)33/h5-9,13-16,23,34-36,50H,3-4,10-12,17-22,24-28,45H2,1-2H3,(H2,46,59)(H,51,61)(H,52,63)(H,53,62)(H,54,60)(H,55,64)(H4,47,48,49)/t34?,35-,36-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 2.00E+3 | n/a | n/a | n/a | n/a |
Utrecht University
Curated by ChEMBL
| Assay Description
Effective concentration against human melanocortin receptor-4 expressed in 293 HEK cells |
J Med Chem 48: 4224-30 (2005)
Article DOI: 10.1021/jm0490033
BindingDB Entry DOI: 10.7270/Q2QV3NQ5 |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 5 (MC5R)
(Mus musculus (Mouse)) | BDBM50410255
(CHEMBL2371828)Show SMILES CCCCN(CC(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N(CC(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCC(N)=O)Cc1ccccc1)C(C)=O |wU:37.37,13.13,26.26,(-9.04,-26.89,;-7.85,-25.9,;-6.41,-26.43,;-5.23,-25.45,;-3.78,-25.98,;-2.6,-24.99,;-1.15,-25.52,;-.89,-27.04,;.03,-24.54,;1.48,-25.07,;2.66,-24.08,;2.4,-22.56,;4.1,-24.61,;5.29,-23.62,;5.02,-22.11,;3.58,-21.58,;3.32,-20.06,;1.87,-19.53,;1.61,-18.01,;6.73,-24.16,;7,-25.67,;7.92,-23.17,;9.36,-23.7,;10.54,-22.71,;11.22,-21.33,;11.99,-23.25,;13.17,-22.26,;12.91,-20.74,;14.09,-19.76,;13.83,-18.24,;15.01,-17.25,;14.75,-15.73,;15.93,-14.75,;13.3,-15.2,;14.62,-22.79,;14.88,-24.31,;15.8,-21.8,;17.25,-22.34,;18.43,-21.35,;19.87,-21.88,;20.29,-23.36,;21.83,-23.42,;22.36,-21.97,;23.79,-21.4,;24.01,-19.88,;22.8,-18.93,;21.37,-19.5,;21.15,-21.02,;17.51,-23.85,;16.33,-24.84,;18.95,-24.38,;19.22,-25.9,;20.66,-26.43,;20.93,-27.95,;21.85,-25.45,;7.65,-21.65,;8.84,-20.67,;8.57,-19.15,;9.76,-18.16,;11.2,-18.69,;11.46,-20.21,;10.28,-21.2,;-3.52,-27.49,;-2.07,-28.03,;-4.7,-28.48,)| Show InChI InChI=1S/C44H65N13O8/c1-3-4-21-56(29(2)58)27-39(61)51-25-38(60)54-35(17-10-11-19-45)43(65)57(26-30-13-6-5-7-14-30)28-40(62)53-34(18-12-20-49-44(47)48)42(64)55-36(41(63)52-24-37(46)59)22-31-23-50-33-16-9-8-15-32(31)33/h5-9,13-16,23,34-36,50H,3-4,10-12,17-22,24-28,45H2,1-2H3,(H2,46,59)(H,51,61)(H,52,63)(H,53,62)(H,54,60)(H,55,64)(H4,47,48,49)/t34?,35-,36-/m0/s1 | UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 5.01E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Utrecht University
Curated by ChEMBL
| Assay Description
Displacement of [125I]NDP-MSH from mouse melanocortin receptor-5 expressed in 293 HEK cells |
J Med Chem 48: 4224-30 (2005)
Article DOI: 10.1021/jm0490033
BindingDB Entry DOI: 10.7270/Q2QV3NQ5 |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 4
(Homo sapiens (Human)) | BDBM50410255
(CHEMBL2371828)Show SMILES CCCCN(CC(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N(CC(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCC(N)=O)Cc1ccccc1)C(C)=O |wU:37.37,13.13,26.26,(-9.04,-26.89,;-7.85,-25.9,;-6.41,-26.43,;-5.23,-25.45,;-3.78,-25.98,;-2.6,-24.99,;-1.15,-25.52,;-.89,-27.04,;.03,-24.54,;1.48,-25.07,;2.66,-24.08,;2.4,-22.56,;4.1,-24.61,;5.29,-23.62,;5.02,-22.11,;3.58,-21.58,;3.32,-20.06,;1.87,-19.53,;1.61,-18.01,;6.73,-24.16,;7,-25.67,;7.92,-23.17,;9.36,-23.7,;10.54,-22.71,;11.22,-21.33,;11.99,-23.25,;13.17,-22.26,;12.91,-20.74,;14.09,-19.76,;13.83,-18.24,;15.01,-17.25,;14.75,-15.73,;15.93,-14.75,;13.3,-15.2,;14.62,-22.79,;14.88,-24.31,;15.8,-21.8,;17.25,-22.34,;18.43,-21.35,;19.87,-21.88,;20.29,-23.36,;21.83,-23.42,;22.36,-21.97,;23.79,-21.4,;24.01,-19.88,;22.8,-18.93,;21.37,-19.5,;21.15,-21.02,;17.51,-23.85,;16.33,-24.84,;18.95,-24.38,;19.22,-25.9,;20.66,-26.43,;20.93,-27.95,;21.85,-25.45,;7.65,-21.65,;8.84,-20.67,;8.57,-19.15,;9.76,-18.16,;11.2,-18.69,;11.46,-20.21,;10.28,-21.2,;-3.52,-27.49,;-2.07,-28.03,;-4.7,-28.48,)| Show InChI InChI=1S/C44H65N13O8/c1-3-4-21-56(29(2)58)27-39(61)51-25-38(60)54-35(17-10-11-19-45)43(65)57(26-30-13-6-5-7-14-30)28-40(62)53-34(18-12-20-49-44(47)48)42(64)55-36(41(63)52-24-37(46)59)22-31-23-50-33-16-9-8-15-32(31)33/h5-9,13-16,23,34-36,50H,3-4,10-12,17-22,24-28,45H2,1-2H3,(H2,46,59)(H,51,61)(H,52,63)(H,53,62)(H,54,60)(H,55,64)(H4,47,48,49)/t34?,35-,36-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 5.01E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Utrecht University
Curated by ChEMBL
| Assay Description
Displacement of [125I]NDP-MSH from human melanocortin receptor-4 expressed in 293 HEK cells |
J Med Chem 48: 4224-30 (2005)
Article DOI: 10.1021/jm0490033
BindingDB Entry DOI: 10.7270/Q2QV3NQ5 |
More data for this
Ligand-Target Pair | |
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