BDBM50410331 CHEMBL193861
SMILES: CC(C)N1CCC(CC1)Oc1ccc(CN2CCN(CC2)c2ccccc2)cc1
InChI Key: InChIKey=OZYQJQRDWKSBHB-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Histamine H3 receptor (Homo sapiens (Human)) | BDBM50410331 (CHEMBL193861) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | 2 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson& Johnson Pharmaceutical Research and Development Curated by ChEMBL | Assay Description Mean binding affinity for human H3 receptor | J Med Chem 48: 2229-38 (2005) Article DOI: 10.1021/jm049212n BindingDB Entry DOI: 10.7270/Q2GB258T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histamine H3 receptor (Homo sapiens (Human)) | BDBM50410331 (CHEMBL193861) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | 1.02 | n/a | n/a | n/a | n/a | n/a |
Johnson& Johnson Pharmaceutical Research and Development Curated by ChEMBL | Assay Description Mean functional activity against human H3 receptor | J Med Chem 48: 2229-38 (2005) Article DOI: 10.1021/jm049212n BindingDB Entry DOI: 10.7270/Q2GB258T | |||||||||||
More data for this Ligand-Target Pair |