BDBM50410345 CHEMBL194548

SMILES: CC(C)N1CCC(CC1)Oc1ccc(CNc2ccccc2)cc1

InChI Key: InChIKey=LBIHKNJGZIBWIY-UHFFFAOYSA-N

Data: 1 KI  1 Kd

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50410345   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H3 receptor (Homo sapiens (Human))	BDBM50410345 (CHEMBL194548) Show SMILES CC(C)N1CCC(CC1)Oc1ccc(CNc2ccccc2)cc1 Show InChI InChI=1S/C21H28N2O/c1-17(2)23-14-12-21(13-15-23)24-20-10-8-18(9-11-20)16-22-19-6-4-3-5-7-19/h3-11,17,21-22H,12-16H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	5.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Mean binding affinity for human H3 receptor				J Med Chem 48: 2229-38 (2005) Article DOI: 10.1021/jm049212n BindingDB Entry DOI: 10.7270/Q2GB258T
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50410345 (CHEMBL194548) Show SMILES CC(C)N1CCC(CC1)Oc1ccc(CNc2ccccc2)cc1 Show InChI InChI=1S/C21H28N2O/c1-17(2)23-14-12-21(13-15-23)24-20-10-8-18(9-11-20)16-22-19-6-4-3-5-7-19/h3-11,17,21-22H,12-16H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	2.69	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Mean functional activity against human H3 receptor				J Med Chem 48: 2229-38 (2005) Article DOI: 10.1021/jm049212n BindingDB Entry DOI: 10.7270/Q2GB258T
					More data for this Ligand-Target Pair