null

SMILES: CN1CCN(CC1)c1nccc2cc3CCN(C(=O)c4cc(C)oc4C(F)(F)F)c3cc12

InChI Key: InChIKey=HLQZOVOBNOQXGW-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50410439   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 1B (Homo sapiens (Human))	BDBM50410439 (CHEMBL199175) Show SMILES CN1CCN(CC1)c1nccc2cc3CCN(C(=O)c4cc(C)oc4C(F)(F)F)c3cc12 Show InChI InChI=1S/C23H23F3N4O2/c1-14-11-18(20(32-14)23(24,25)26)22(31)30-6-4-16-12-15-3-5-27-21(17(15)13-19(16)30)29-9-7-28(2)8-10-29/h3,5,11-13H,4,6-10H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Mean binding affinity towards 5-hydroxytryptamine 1B receptor using [3H]5-HT or [3H]-8-OH-DPAT as the radioligand				Bioorg Med Chem Lett 15: 4370-4 (2005) Article DOI: 10.1016/j.bmcl.2005.06.042 BindingDB Entry DOI: 10.7270/Q2319X3T
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50410439 (CHEMBL199175) Show SMILES CN1CCN(CC1)c1nccc2cc3CCN(C(=O)c4cc(C)oc4C(F)(F)F)c3cc12 Show InChI InChI=1S/C23H23F3N4O2/c1-14-11-18(20(32-14)23(24,25)26)22(31)30-6-4-16-12-15-3-5-27-21(17(15)13-19(16)30)29-9-7-28(2)8-10-29/h3,5,11-13H,4,6-10H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	5.01	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Mean binding affinity towards 5-hydroxytryptamine 1A receptor using [3H]-5-HT or [3H]8-OH-DPAT as the radioligand				Bioorg Med Chem Lett 15: 4370-4 (2005) Article DOI: 10.1016/j.bmcl.2005.06.042 BindingDB Entry DOI: 10.7270/Q2319X3T
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1D (Homo sapiens (Human))	BDBM50410439 (CHEMBL199175) Show SMILES CN1CCN(CC1)c1nccc2cc3CCN(C(=O)c4cc(C)oc4C(F)(F)F)c3cc12 Show InChI InChI=1S/C23H23F3N4O2/c1-14-11-18(20(32-14)23(24,25)26)22(31)30-6-4-16-12-15-3-5-27-21(17(15)13-19(16)30)29-9-7-28(2)8-10-29/h3,5,11-13H,4,6-10H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	7.94	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Mean binding affinity towards 5-hydroxytryptamine 1D receptor using [3H]5-HT or [3H]-8-OH-DPAT as the radioligand				Bioorg Med Chem Lett 15: 4370-4 (2005) Article DOI: 10.1016/j.bmcl.2005.06.042 BindingDB Entry DOI: 10.7270/Q2319X3T
					More data for this Ligand-Target Pair