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BDBM50410555 CHEMBL373050

SMILES: CC1(CCCCC1)c1nc(CCC23CC4CC(CC(C4)C2)C3)c([nH]1)C(=O)Nc1cccc(c1)C(O)=O

InChI Key: InChIKey=SENALJXYBWJQJJ-UHFFFAOYSA-N

Data: 1 Kd

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50410555   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
CCKBR


(RAT)		BDBM50410555
PNG
(CHEMBL373050)
Show SMILES CC1(CCCCC1)c1nc(CCC23CC4CC(CC(C4)C2)C3)c([nH]1)C(=O)Nc1cccc(c1)C(O)=O |TLB:15:16:20:14.13.19,19:18:21:14.13.15,19:14:21:18.20.17,THB:15:14:20:16.21.17,17:18:13:16.21.15,17:16:13:18.20.19|
Show InChI InChI=1S/C30H39N3O3/c1-29(9-3-2-4-10-29)28-32-24(8-11-30-16-19-12-20(17-30)14-21(13-19)18-30)25(33-28)26(34)31-23-7-5-6-22(15-23)27(35)36/h5-7,15,19-21H,2-4,8-14,16-18H2,1H3,(H,31,34)(H,32,33)(H,35,36)
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UniProtKB/SwissProt

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PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/an/a 1.62n/an/an/an/an/a



James Black Foundation

Curated by ChEMBL


Assay Description
Antagonist activity against CCK2 receptor estimated from single shifts of pentagastrin concentration-effect curves in the isolated rat stomach

J Med Chem 48: 6803-12 (2005)


Article DOI: 10.1021/jm0490686
BindingDB Entry DOI: 10.7270/Q2PV6MM7
More data for this
Ligand-Target Pair