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BDBM50410873 CHEMBL383292

SMILES: COc1nc2ccccc2nc1C(=O)Nc1cc(CN2CCCC2)c(O)c(c1)N1CCCC1

InChI Key: InChIKey=LRCAPUZYLLCAIN-UHFFFAOYSA-N

Data: 1 Kd

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50410873   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
5-hydroxytryptamine receptor 3A


(GUINEA PIG)		BDBM50410873
PNG
(CHEMBL383292)
Show SMILES COc1nc2ccccc2nc1C(=O)Nc1cc(CN2CCCC2)c(O)c(c1)N1CCCC1
Show InChI InChI=1S/C25H29N5O3/c1-33-25-22(27-19-8-2-3-9-20(19)28-25)24(32)26-18-14-17(16-29-10-4-5-11-29)23(31)21(15-18)30-12-6-7-13-30/h2-3,8-9,14-15,31H,4-7,10-13,16H2,1H3,(H,26,32)
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Similars
Article
PubMed
n/an/an/a>1.00E+6n/an/an/an/an/a



Periyar College of Pharmaceutical Sciences for Girls

Curated by ChEMBL


Assay Description
Antagonist effect against 2-methyl-5-HT activity at 5-HT3 receptor in longitudinal muscle myenteric plexus from guinea pig ileum

Bioorg Med Chem Lett 16: 2769-72 (2006)


Article DOI: 10.1016/j.bmcl.2006.02.006
BindingDB Entry DOI: 10.7270/Q2MW2JCG
More data for this
Ligand-Target Pair