BDBM50410908 CHEMBL381931
SMILES: CC(C)C[C@H](NC(=O)[C@H](C)NC(=O)[C@H](COCc1cccc(Cl)c1)NS(=O)(=O)c1ccc(C)cc1)C(=O)c1nnc(o1)-c1ccccc1
InChI Key: InChIKey=HTRXOQVDRFGNCE-OIFPXGRLSA-N
Data: 1 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
20S proteasome chymotrypsin-like (Homo sapiens (Human)) | BDBM50410908 (CHEMBL381931) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 140 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Celera Curated by ChEMBL | Assay Description Inhibition of chymotrypsin-like proteasome activity of human 20S proteasome | J Med Chem 49: 2953-68 (2006) Article DOI: 10.1021/jm058289o BindingDB Entry DOI: 10.7270/Q2FF3S0S | |||||||||||
More data for this Ligand-Target Pair |