BDBM50411000 CHEMBL558178

SMILES: CCCCCC(=O)N[C@@H](CCCCN)C(=O)c1noc(Cc2ccc(OCCc3ccc(Cl)c(Cl)c3)cc2)n1

InChI Key: InChIKey=DOSXWQFAKWWFPY-VWLOTQADSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50411000   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tryptase (Homo sapiens (Human))	BDBM50411000 (CHEMBL558178) Show SMILES CCCCCC(=O)N[C@@H](CCCCN)C(=O)c1noc(Cc2ccc(OCCc3ccc(Cl)c(Cl)c3)cc2)n1 |r| Show InChI InChI=1S/C29H36Cl2N4O4/c1-2-3-4-8-26(36)33-25(7-5-6-16-32)28(37)29-34-27(39-35-29)19-20-9-12-22(13-10-20)38-17-15-21-11-14-23(30)24(31)18-21/h9-14,18,25H,2-8,15-17,19,32H2,1H3,(H,33,36)/t25-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	9.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Celera Genomics Curated by ChEMBL					Assay Description Inhibition of human B tryptase				Bioorg Med Chem Lett 16: 3434-9 (2006) Article DOI: 10.1016/j.bmcl.2006.04.013 BindingDB Entry DOI: 10.7270/Q2G44RHP
					More data for this Ligand-Target Pair