BDBM50411042 CHEMBL377176

SMILES: Cc1noc(=O)c2ccc(NC(=O)C(O)(CC3CCCc4c3cccc4[N+]([O-])=O)C(F)(F)F)cc12

InChI Key: InChIKey=BFPGMZNBQDECJA-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50411042   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50411042 (CHEMBL377176) Show SMILES Cc1noc(=O)c2ccc(NC(=O)C(O)(CC3CCCc4c3cccc4[N+]([O-])=O)C(F)(F)F)cc12 Show InChI InChI=1S/C23H20F3N3O6/c1-12-18-10-14(8-9-17(18)20(30)35-28-12)27-21(31)22(32,23(24,25)26)11-13-4-2-6-16-15(13)5-3-7-19(16)29(33)34/h3,5,7-10,13,32H,2,4,6,11H2,1H3,(H,27,31)	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Medicines Research Centre Curated by ChEMBL					Assay Description Inhibition of fluorescent-labeled Dexamethasone binding to GR				J Med Chem 49: 4216-31 (2006) Checked by Author Article DOI: 10.1021/jm060302x BindingDB Entry DOI: 10.7270/Q2BC40SB
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50411042 (CHEMBL377176) Show SMILES Cc1noc(=O)c2ccc(NC(=O)C(O)(CC3CCCc4c3cccc4[N+]([O-])=O)C(F)(F)F)cc12 Show InChI InChI=1S/C23H20F3N3O6/c1-12-18-10-14(8-9-17(18)20(30)35-28-12)27-21(31)22(32,23(24,25)26)11-13-4-2-6-16-15(13)5-3-7-19(16)29(33)34/h3,5,7-10,13,32H,2,4,6,11H2,1H3,(H,27,31)	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	<1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Medicines Research Centre Curated by ChEMBL					Assay Description Agonist activity at GR assessed as NF-kappaB-mediated transrepression of secreted placental alkaline phosphatase gene in human A549 cells				J Med Chem 49: 4216-31 (2006) Checked by Author Article DOI: 10.1021/jm060302x BindingDB Entry DOI: 10.7270/Q2BC40SB
					More data for this Ligand-Target Pair