BDBM50412227 CHEMBL480181

SMILES: Cc1cc(nn1Cc1cc(Cl)ccc1OCc1ccccc1)C(=O)Nc1ccc(CN2CCCCC2)cc1

InChI Key: InChIKey=DBJFGLLLLSGPOT-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50412227   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin E2 receptor EP1 subtype (EP1) (Homo sapiens (Human))	BDBM50412227 (CHEMBL480181) Show SMILES Cc1cc(nn1Cc1cc(Cl)ccc1OCc1ccccc1)C(=O)Nc1ccc(CN2CCCCC2)cc1 Show InChI InChI=1S/C31H33ClN4O2/c1-23-18-29(31(37)33-28-13-10-24(11-14-28)20-35-16-6-3-7-17-35)34-36(23)21-26-19-27(32)12-15-30(26)38-22-25-8-4-2-5-9-25/h2,4-5,8-15,18-19H,3,6-7,16-17,20-22H2,1H3,(H,33,37)	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	12.6	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Displacement of [H3PGE2 from human EP1 receptor expressed in CHOK1 cells				Bioorg Med Chem Lett 18: 4027-32 (2008) Article DOI: 10.1016/j.bmcl.2008.05.118 BindingDB Entry DOI: 10.7270/Q2NC62F7
					More data for this Ligand-Target Pair