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BDBM50412230 CHEMBL480790

SMILES: CCNCc1ccc(NC(=O)c2cc(C)n(Cc3cc(Cl)ccc3OCc3ccccc3)n2)cc1

InChI Key: InChIKey=PEMSPDCFSXJZNL-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50412230   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Prostaglandin E2 receptor EP1 subtype (EP1)


(Homo sapiens (Human))
BDBM50412230
PNG
(CHEMBL480790)
Show SMILES CCNCc1ccc(NC(=O)c2cc(C)n(Cc3cc(Cl)ccc3OCc3ccccc3)n2)cc1
Show InChI InChI=1S/C28H29ClN4O2/c1-3-30-17-21-9-12-25(13-10-21)31-28(34)26-15-20(2)33(32-26)18-23-16-24(29)11-14-27(23)35-19-22-7-5-4-6-8-22/h4-16,30H,3,17-19H2,1-2H3,(H,31,34)
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 12.6n/an/an/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Displacement of [H3PGE2 from human EP1 receptor expressed in CHOK1 cells


Bioorg Med Chem Lett 18: 4027-32 (2008)


Article DOI: 10.1016/j.bmcl.2008.05.118
BindingDB Entry DOI: 10.7270/Q2NC62F7
More data for this
Ligand-Target Pair