BDBM50412238 CHEMBL523158

SMILES: CCNCc1ccc(NC(=O)c2cc(C)n(Cc3cc(Cl)ccc3OCC(C)C)n2)cc1

InChI Key: InChIKey=XGIYAKFXYPMMRH-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50412238   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin E2 receptor EP1 subtype (EP1) (Homo sapiens (Human))	BDBM50412238 (CHEMBL523158) Show SMILES CCNCc1ccc(NC(=O)c2cc(C)n(Cc3cc(Cl)ccc3OCC(C)C)n2)cc1 Show InChI InChI=1S/C25H31ClN4O2/c1-5-27-14-19-6-9-22(10-7-19)28-25(31)23-12-18(4)30(29-23)15-20-13-21(26)8-11-24(20)32-16-17(2)3/h6-13,17,27H,5,14-16H2,1-4H3,(H,28,31)	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.94	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Displacement of [H3PGE2 from human EP1 receptor expressed in CHOK1 cells				Bioorg Med Chem Lett 18: 4027-32 (2008) Article DOI: 10.1016/j.bmcl.2008.05.118 BindingDB Entry DOI: 10.7270/Q2NC62F7
					More data for this Ligand-Target Pair