BDBM50412260 CHEMBL273485

SMILES: CC(Oc1ccccc1)C1=NCCN1

InChI Key: InChIKey=MDFFTELFADBPIZ-UHFFFAOYSA-N

Data: 14 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 14 hits for monomerid = 50412260   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Alpha-2A adrenergic receptor (Homo sapiens (Human))	BDBM50412260 (CHEMBL273485) Show SMILES CC(Oc1ccccc1)C1=NCCN1 |t:10| Show InChI InChI=1S/C11H14N2O/c1-9(11-12-7-8-13-11)14-10-5-3-2-4-6-10/h2-6,9H,7-8H2,1H3,(H,12,13)	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	27	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Camerino Curated by ChEMBL					Assay Description Displacement of [3H]RS79948-197 from human recombinant adrenergic alpha2A receptor expressed in CHO cells				J Med Chem 51: 4289-99 (2008) Article DOI: 10.1021/jm800250z BindingDB Entry DOI: 10.7270/Q2HQ4147
					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor (Homo sapiens (Human))	BDBM50412260 (CHEMBL273485) Show SMILES CC(Oc1ccccc1)C1=NCCN1 |t:10| Show InChI InChI=1S/C11H14N2O/c1-9(11-12-7-8-13-11)14-10-5-3-2-4-6-10/h2-6,9H,7-8H2,1H3,(H,12,13)	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	27	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita` di Camerino Curated by ChEMBL					Assay Description Displacement of [3H]RX821002 from human alpha2A adrenoceptor expressed in CHO cells				J Med Chem 53: 7825-35 (2010) Article DOI: 10.1021/jm100977d BindingDB Entry DOI: 10.7270/Q24B32JF
					More data for this Ligand-Target Pair
Adrenergic receptor alpha-2 (RAT-NEONATAL RAT-Rattus norvegicus (rat))	BDBM50412260 (CHEMBL273485) Show SMILES CC(Oc1ccccc1)C1=NCCN1 |t:10| Show InChI InChI=1S/C11H14N2O/c1-9(11-12-7-8-13-11)14-10-5-3-2-4-6-10/h2-6,9H,7-8H2,1H3,(H,12,13)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	98	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Camerino Curated by ChEMBL					Assay Description Displacement of [3H]clonidine from rat cortex membrane Alpha-2 adrenergic receptors				J Med Chem 46: 2169-76 (2003) Article DOI: 10.1021/jm021113r BindingDB Entry DOI: 10.7270/Q2HH6NSW
					More data for this Ligand-Target Pair
Adrenergic receptor alpha-2 (RAT-NEONATAL RAT-Rattus norvegicus (rat))	BDBM50412260 (CHEMBL273485) Show SMILES CC(Oc1ccccc1)C1=NCCN1 |t:10| Show InChI InChI=1S/C11H14N2O/c1-9(11-12-7-8-13-11)14-10-5-3-2-4-6-10/h2-6,9H,7-8H2,1H3,(H,12,13)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	98	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Camerino Curated by ChEMBL					Assay Description Displacement of [3H]clonidine from Alpha-2 adrenergic receptor of rat cortex membrane				J Med Chem 45: 32-40 (2002) Article DOI: 10.1021/jm0110082 BindingDB Entry DOI: 10.7270/Q21N83VZ
					More data for this Ligand-Target Pair
Alpha-2B adrenergic receptor (Homo sapiens (Human))	BDBM50412260 (CHEMBL273485) Show SMILES CC(Oc1ccccc1)C1=NCCN1 |t:10| Show InChI InChI=1S/C11H14N2O/c1-9(11-12-7-8-13-11)14-10-5-3-2-4-6-10/h2-6,9H,7-8H2,1H3,(H,12,13)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	166	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita` di Camerino Curated by ChEMBL					Assay Description Displacement of [3H]RX821002 from human alpha2B adrenoceptor expressed in CHO cells				J Med Chem 53: 7825-35 (2010) Article DOI: 10.1021/jm100977d BindingDB Entry DOI: 10.7270/Q24B32JF
					More data for this Ligand-Target Pair
Alpha-2B adrenergic receptor (Homo sapiens (Human))	BDBM50412260 (CHEMBL273485) Show SMILES CC(Oc1ccccc1)C1=NCCN1 |t:10| Show InChI InChI=1S/C11H14N2O/c1-9(11-12-7-8-13-11)14-10-5-3-2-4-6-10/h2-6,9H,7-8H2,1H3,(H,12,13)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	166	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Camerino Curated by ChEMBL					Assay Description Displacement of [3H]RS79948-197 from human recombinant adrenergic alpha2B receptor expressed in CHO cells				J Med Chem 51: 4289-99 (2008) Article DOI: 10.1021/jm800250z BindingDB Entry DOI: 10.7270/Q2HQ4147
					More data for this Ligand-Target Pair
Alpha-2C adrenergic receptor (Homo sapiens (Human))	BDBM50412260 (CHEMBL273485) Show SMILES CC(Oc1ccccc1)C1=NCCN1 |t:10| Show InChI InChI=1S/C11H14N2O/c1-9(11-12-7-8-13-11)14-10-5-3-2-4-6-10/h2-6,9H,7-8H2,1H3,(H,12,13)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	263	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita` di Camerino Curated by ChEMBL					Assay Description Displacement of [3H]RX821002 from human Alpha-2C adrenoceptor expressed in CHO cells				J Med Chem 53: 7825-35 (2010) Article DOI: 10.1021/jm100977d BindingDB Entry DOI: 10.7270/Q24B32JF
					More data for this Ligand-Target Pair
Alpha-2C adrenergic receptor (Homo sapiens (Human))	BDBM50412260 (CHEMBL273485) Show SMILES CC(Oc1ccccc1)C1=NCCN1 |t:10| Show InChI InChI=1S/C11H14N2O/c1-9(11-12-7-8-13-11)14-10-5-3-2-4-6-10/h2-6,9H,7-8H2,1H3,(H,12,13)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	263	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Camerino Curated by ChEMBL					Assay Description Displacement of [3H]RS79948-197 from human recombinant adrenergic Alpha-2C receptor expressed in CHO cells				J Med Chem 51: 4289-99 (2008) Article DOI: 10.1021/jm800250z BindingDB Entry DOI: 10.7270/Q2HQ4147
					More data for this Ligand-Target Pair
Imidazoline I1 (RAT)	BDBM50412260 (CHEMBL273485) Show SMILES CC(Oc1ccccc1)C1=NCCN1 |t:10| Show InChI InChI=1S/C11H14N2O/c1-9(11-12-7-8-13-11)14-10-5-3-2-4-6-10/h2-6,9H,7-8H2,1H3,(H,12,13)	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	309	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Belgrade Curated by ChEMBL					Assay Description Displacement of [125I]PIC from Imidazoline-1 receptor in rat PC12 cell membrane by gamma counting method				Bioorg Med Chem 24: 3174-83 (2016) BindingDB Entry DOI: 10.7270/Q2NZ89J3
					More data for this Ligand-Target Pair
Nischarin (RAT)	BDBM50412260 (CHEMBL273485) Show SMILES CC(Oc1ccccc1)C1=NCCN1 |t:10| Show InChI InChI=1S/C11H14N2O/c1-9(11-12-7-8-13-11)14-10-5-3-2-4-6-10/h2-6,9H,7-8H2,1H3,(H,12,13)	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	309	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Camerino Curated by ChEMBL					Assay Description Displacement of [125I]-p-iodoclonidin from I1-imidazoline receptor in rat PC12 cell membranes				ACS Med Chem Lett 6: 496-501 (2015) Article DOI: 10.1021/acsmedchemlett.5b00115 BindingDB Entry DOI: 10.7270/Q20C4XGC
					More data for this Ligand-Target Pair
Nischarin (Homo sapiens (Human))	BDBM50412260 (CHEMBL273485) Show SMILES CC(Oc1ccccc1)C1=NCCN1 |t:10| Show InChI InChI=1S/C11H14N2O/c1-9(11-12-7-8-13-11)14-10-5-3-2-4-6-10/h2-6,9H,7-8H2,1H3,(H,12,13)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	309	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Camerino Curated by ChEMBL					Assay Description Displacement of [125I]p-iodoclonidine from imidazoline receptor I-1 in rat pheochromocytoma cells				J Med Chem 46: 2169-76 (2003) Article DOI: 10.1021/jm021113r BindingDB Entry DOI: 10.7270/Q2HH6NSW
					More data for this Ligand-Target Pair
Nischarin (Homo sapiens (Human))	BDBM50412260 (CHEMBL273485) Show SMILES CC(Oc1ccccc1)C1=NCCN1 |t:10| Show InChI InChI=1S/C11H14N2O/c1-9(11-12-7-8-13-11)14-10-5-3-2-4-6-10/h2-6,9H,7-8H2,1H3,(H,12,13)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.51E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ d'Orl£ans Curated by ChEMBL					Assay Description Binding affinity for imidazoline receptor I-2 in rabbit kidney homogenate (relative to [3H]-Idazoxan radioligand)				J Med Chem 43: 1109-22 (2000) Article DOI: 10.1021/jm991124t BindingDB Entry DOI: 10.7270/Q2SB48G9
					More data for this Ligand-Target Pair
Imidazoline I2-receptor (Homo sapiens (Human))	BDBM50412260 (CHEMBL273485) Show SMILES CC(Oc1ccccc1)C1=NCCN1 |t:10| Show InChI InChI=1S/C11H14N2O/c1-9(11-12-7-8-13-11)14-10-5-3-2-4-6-10/h2-6,9H,7-8H2,1H3,(H,12,13)	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.69E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Camerino Curated by ChEMBL					Assay Description Displacement of [3H]idazoxan from imidazoline receptor I-2 of rabbit kidney membranes				J Med Chem 46: 2169-76 (2003) Article DOI: 10.1021/jm021113r BindingDB Entry DOI: 10.7270/Q2HH6NSW
					More data for this Ligand-Target Pair
Imidazoline I2-receptor (Homo sapiens (Human))	BDBM50412260 (CHEMBL273485) Show SMILES CC(Oc1ccccc1)C1=NCCN1 |t:10| Show InChI InChI=1S/C11H14N2O/c1-9(11-12-7-8-13-11)14-10-5-3-2-4-6-10/h2-6,9H,7-8H2,1H3,(H,12,13)	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.69E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Camerino Curated by ChEMBL					Assay Description Displacement of [3H]idazoxan from imidazoline receptor I-2 binding sites in rabbit kidney membrane				J Med Chem 45: 32-40 (2002) Article DOI: 10.1021/jm0110082 BindingDB Entry DOI: 10.7270/Q21N83VZ
					More data for this Ligand-Target Pair