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SMILES: CCn1ncc2c(NC3CCOCC3)c(cnc12)C(=O)NC1CCN(CC1)C(C)=O

InChI Key: InChIKey=PESOMZWNWQBAOB-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50412407   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
cAMP-specific 3',5'-cyclic phosphodiesterase 4B


(Homo sapiens (Human))		BDBM50412407
PNG
(CHEMBL488633)
Show SMILES CCn1ncc2c(NC3CCOCC3)c(cnc12)C(=O)NC1CCN(CC1)C(C)=O
Show InChI InChI=1S/C21H30N6O3/c1-3-27-20-17(13-23-27)19(24-16-6-10-30-11-7-16)18(12-22-20)21(29)25-15-4-8-26(9-5-15)14(2)28/h12-13,15-16H,3-11H2,1-2H3,(H,22,24)(H,25,29)
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Article
PubMed
n/an/a 126n/an/an/an/an/an/a



GlaxoSmithKline Medicines Research Centre

Curated by ChEMBL


Assay Description
Inhibition of human PDE4B in Sf9 cells

Bioorg Med Chem Lett 18: 4237-41 (2008)


Article DOI: 10.1016/j.bmcl.2008.05.052
BindingDB Entry DOI: 10.7270/Q2ZP47B3
More data for this
Ligand-Target Pair