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SMILES: CCn1ncc2c(NC3CCOCC3)c(cnc12)C(=O)NC1CCCC1

InChI Key: InChIKey=ZLEDFOJPRPLJAJ-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50412408   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
cAMP-specific 3',5'-cyclic phosphodiesterase 4B


(Homo sapiens (Human))		BDBM50412408
PNG
(CHEMBL488632)
Show SMILES CCn1ncc2c(NC3CCOCC3)c(cnc12)C(=O)NC1CCCC1
Show InChI InChI=1S/C19H27N5O2/c1-2-24-18-15(12-21-24)17(22-14-7-9-26-10-8-14)16(11-20-18)19(25)23-13-5-3-4-6-13/h11-14H,2-10H2,1H3,(H,20,22)(H,23,25)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 50.1n/an/an/an/an/an/a



GlaxoSmithKline Medicines Research Centre

Curated by ChEMBL


Assay Description
Inhibition of human PDE4B in Sf9 cells

Bioorg Med Chem Lett 18: 4237-41 (2008)


Article DOI: 10.1016/j.bmcl.2008.05.052
BindingDB Entry DOI: 10.7270/Q2ZP47B3
More data for this
Ligand-Target Pair