Found 4 hits for monomerid = 50412437 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Sodium-dependent serotonin transporter
(Rattus norvegicus (rat)) | BDBM50412437
(CHEMBL484742)Show SMILES Cc1ccc2c(OC3CCN(Cc4ccc5OCC(=O)Nc5c4)CC3)cccc2n1 Show InChI InChI=1S/C24H25N3O3/c1-16-5-7-19-20(25-16)3-2-4-22(19)30-18-9-11-27(12-10-18)14-17-6-8-23-21(13-17)26-24(28)15-29-23/h2-8,13,18H,9-12,14-15H2,1H3,(H,26,28) | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 200 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description Inhibition of [3H]5HT reuptake at SERT in rat cortical synaptosomes |
Bioorg Med Chem Lett 18: 5581-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.08.110 BindingDB Entry DOI: 10.7270/Q2KH0PKZ |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 1D
(Homo sapiens (Human)) | BDBM50412437
(CHEMBL484742)Show SMILES Cc1ccc2c(OC3CCN(Cc4ccc5OCC(=O)Nc5c4)CC3)cccc2n1 Show InChI InChI=1S/C24H25N3O3/c1-16-5-7-19-20(25-16)3-2-4-22(19)30-18-9-11-27(12-10-18)14-17-6-8-23-21(13-17)26-24(28)15-29-23/h2-8,13,18H,9-12,14-15H2,1H3,(H,26,28) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 1.26E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description Displacement of [3H]5HT from human cloned 5HT1D receptor expressed in CHO cells |
Bioorg Med Chem Lett 18: 5581-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.08.110 BindingDB Entry DOI: 10.7270/Q2KH0PKZ |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 1B
(Homo sapiens (Human)) | BDBM50412437
(CHEMBL484742)Show SMILES Cc1ccc2c(OC3CCN(Cc4ccc5OCC(=O)Nc5c4)CC3)cccc2n1 Show InChI InChI=1S/C24H25N3O3/c1-16-5-7-19-20(25-16)3-2-4-22(19)30-18-9-11-27(12-10-18)14-17-6-8-23-21(13-17)26-24(28)15-29-23/h2-8,13,18H,9-12,14-15H2,1H3,(H,26,28) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| >2.51E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description Displacement of [3H]5HT from human cloned 5HT1B receptor expressed in CHO cells |
Bioorg Med Chem Lett 18: 5581-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.08.110 BindingDB Entry DOI: 10.7270/Q2KH0PKZ |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 1A
(Homo sapiens (Human)) | BDBM50412437
(CHEMBL484742)Show SMILES Cc1ccc2c(OC3CCN(Cc4ccc5OCC(=O)Nc5c4)CC3)cccc2n1 Show InChI InChI=1S/C24H25N3O3/c1-16-5-7-19-20(25-16)3-2-4-22(19)30-18-9-11-27(12-10-18)14-17-6-8-23-21(13-17)26-24(28)15-29-23/h2-8,13,18H,9-12,14-15H2,1H3,(H,26,28) | PDB
UniProtKB/SwissProt UniProtKB/TrEMBL
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description Displacement of [3H]5HT from human cloned 5HT1A receptor expressed in CHO cells |
Bioorg Med Chem Lett 18: 5581-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.08.110 BindingDB Entry DOI: 10.7270/Q2KH0PKZ |
More data for this Ligand-Target Pair | |