Found 4 hits for monomerid = 50412444 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kcal/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
5-hydroxytryptamine receptor 1D
(Homo sapiens (Human)) | BDBM50412444
(CHEMBL485427)Show SMILES Cc1ccc2c(OC3CCN(CCc4ccc5OCC(=O)Nc5c4)CC3)cccc2n1 Show InChI InChI=1S/C25H27N3O3/c1-17-5-7-20-21(26-17)3-2-4-23(20)31-19-10-13-28(14-11-19)12-9-18-6-8-24-22(15-18)27-25(29)16-30-24/h2-8,15,19H,9-14,16H2,1H3,(H,27,29) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 6.31 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Displacement of [3H]5HT from human cloned 5HT1D receptor expressed in CHO cells |
Bioorg Med Chem Lett 18: 5581-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.08.110
BindingDB Entry DOI: 10.7270/Q2KH0PKZ |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 1B
(Homo sapiens (Human)) | BDBM50412444
(CHEMBL485427)Show SMILES Cc1ccc2c(OC3CCN(CCc4ccc5OCC(=O)Nc5c4)CC3)cccc2n1 Show InChI InChI=1S/C25H27N3O3/c1-17-5-7-20-21(26-17)3-2-4-23(20)31-19-10-13-28(14-11-19)12-9-18-6-8-24-22(15-18)27-25(29)16-30-24/h2-8,15,19H,9-14,16H2,1H3,(H,27,29) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 25.1 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Displacement of [3H]5HT from human cloned 5HT1B receptor expressed in CHO cells |
Bioorg Med Chem Lett 18: 5581-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.08.110
BindingDB Entry DOI: 10.7270/Q2KH0PKZ |
More data for this
Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Rattus norvegicus (rat)) | BDBM50412444
(CHEMBL485427)Show SMILES Cc1ccc2c(OC3CCN(CCc4ccc5OCC(=O)Nc5c4)CC3)cccc2n1 Show InChI InChI=1S/C25H27N3O3/c1-17-5-7-20-21(26-17)3-2-4-23(20)31-19-10-13-28(14-11-19)12-9-18-6-8-24-22(15-18)27-25(29)16-30-24/h2-8,15,19H,9-14,16H2,1H3,(H,27,29) | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 100 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Inhibition of [3H]5HT reuptake at SERT in rat cortical synaptosomes |
Bioorg Med Chem Lett 18: 5581-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.08.110
BindingDB Entry DOI: 10.7270/Q2KH0PKZ |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 1A
(Homo sapiens (Human)) | BDBM50412444
(CHEMBL485427)Show SMILES Cc1ccc2c(OC3CCN(CCc4ccc5OCC(=O)Nc5c4)CC3)cccc2n1 Show InChI InChI=1S/C25H27N3O3/c1-17-5-7-20-21(26-17)3-2-4-23(20)31-19-10-13-28(14-11-19)12-9-18-6-8-24-22(15-18)27-25(29)16-30-24/h2-8,15,19H,9-14,16H2,1H3,(H,27,29) | PDB
UniProtKB/SwissProt
UniProtKB/TrEMBL
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 316 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Displacement of [3H]5HT from human cloned 5HT1A receptor expressed in CHO cells |
Bioorg Med Chem Lett 18: 5581-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.08.110
BindingDB Entry DOI: 10.7270/Q2KH0PKZ |
More data for this
Ligand-Target Pair | |
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