BDBM50412459 CHEMBL212775

SMILES: CN(Cc1ccc(cc1)-c1ccc(CN(C)C2CCCCC2)cc1)C1CCCCC1

InChI Key: InChIKey=QDVWETVNLSAZBK-UHFFFAOYSA-N

Data: 5 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50412459   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H3 receptor (Homo sapiens (Human))	BDBM50412459 (CHEMBL212775) Show SMILES CN(Cc1ccc(cc1)-c1ccc(CN(C)C2CCCCC2)cc1)C1CCCCC1 Show InChI InChI=1S/C28H40N2/c1-29(27-9-5-3-6-10-27)21-23-13-17-25(18-14-23)26-19-15-24(16-20-26)22-30(2)28-11-7-4-8-12-28/h13-20,27-28H,3-12,21-22H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	37	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Parma Curated by ChEMBL					Assay Description Displacement of [3H]RAMHA from human histamine H3 receptor transfected in SK-N-MC cells				Bioorg Med Chem Lett 16: 4063-7 (2006) Article DOI: 10.1016/j.bmcl.2006.04.092 BindingDB Entry DOI: 10.7270/Q2FX7D7Q
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50412459 (CHEMBL212775) Show SMILES CN(Cc1ccc(cc1)-c1ccc(CN(C)C2CCCCC2)cc1)C1CCCCC1 Show InChI InChI=1S/C28H40N2/c1-29(27-9-5-3-6-10-27)21-23-13-17-25(18-14-23)26-19-15-24(16-20-26)22-30(2)28-11-7-4-8-12-28/h13-20,27-28H,3-12,21-22H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	37.1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Parma Curated by ChEMBL					Assay Description Displacement of [3H]RAMHA from human histamine H3 receptor expressed in SK-N-MC cells				Bioorg Med Chem 16: 9911-24 (2008) Article DOI: 10.1016/j.bmc.2008.10.029 BindingDB Entry DOI: 10.7270/Q2FQ9XVP
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50412459 (CHEMBL212775) Show SMILES CN(Cc1ccc(cc1)-c1ccc(CN(C)C2CCCCC2)cc1)C1CCCCC1 Show InChI InChI=1S/C28H40N2/c1-29(27-9-5-3-6-10-27)21-23-13-17-25(18-14-23)26-19-15-24(16-20-26)22-30(2)28-11-7-4-8-12-28/h13-20,27-28H,3-12,21-22H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	214	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Parma Curated by ChEMBL					Assay Description Displacement of [3H]RAMHA from histamine H3 receptor in Wistar rat brain membrane				Bioorg Med Chem 16: 9911-24 (2008) Article DOI: 10.1016/j.bmc.2008.10.029 BindingDB Entry DOI: 10.7270/Q2FQ9XVP
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50412459 (CHEMBL212775) Show SMILES CN(Cc1ccc(cc1)-c1ccc(CN(C)C2CCCCC2)cc1)C1CCCCC1 Show InChI InChI=1S/C28H40N2/c1-29(27-9-5-3-6-10-27)21-23-13-17-25(18-14-23)26-19-15-24(16-20-26)22-30(2)28-11-7-4-8-12-28/h13-20,27-28H,3-12,21-22H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	214	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Parma Curated by ChEMBL					Assay Description Displacement of [3H]RAMHA from histamine H3 receptor in rat brain membranes				Bioorg Med Chem Lett 16: 4063-7 (2006) Article DOI: 10.1016/j.bmcl.2006.04.092 BindingDB Entry DOI: 10.7270/Q2FX7D7Q
					More data for this Ligand-Target Pair
Histamine H4 receptor (Homo sapiens (Human))	BDBM50412459 (CHEMBL212775) Show SMILES CN(Cc1ccc(cc1)-c1ccc(CN(C)C2CCCCC2)cc1)C1CCCCC1 Show InChI InChI=1S/C28H40N2/c1-29(27-9-5-3-6-10-27)21-23-13-17-25(18-14-23)26-19-15-24(16-20-26)22-30(2)28-11-7-4-8-12-28/h13-20,27-28H,3-12,21-22H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6.46E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Parma Curated by ChEMBL					Assay Description Displacement of [3H]RAMHA from human histamine H4 receptor expressed in SK-N-MC cells				Bioorg Med Chem 16: 9911-24 (2008) Article DOI: 10.1016/j.bmc.2008.10.029 BindingDB Entry DOI: 10.7270/Q2FQ9XVP
					More data for this Ligand-Target Pair
Acetylcholinesterase (Rattus norvegicus (rat))	BDBM50412459 (CHEMBL212775) Show SMILES CN(Cc1ccc(cc1)-c1ccc(CN(C)C2CCCCC2)cc1)C1CCCCC1 Show InChI InChI=1S/C28H40N2/c1-29(27-9-5-3-6-10-27)21-23-13-17-25(18-14-23)26-19-15-24(16-20-26)22-30(2)28-11-7-4-8-12-28/h13-20,27-28H,3-12,21-22H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.66E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Parma Curated by ChEMBL					Assay Description Inhibition of acetylcholinesterase in Wistar rat brain homogenate by Ellman's method				Bioorg Med Chem 16: 9911-24 (2008) Article DOI: 10.1016/j.bmc.2008.10.029 BindingDB Entry DOI: 10.7270/Q2FQ9XVP
					More data for this Ligand-Target Pair