BDBM50412466 CHEMBL211486

SMILES: C(NC1CCCCC1)c1ccc(cc1)-c1ccc(CN2CCCCC2)cc1

InChI Key: InChIKey=MGEHNFSMBKQYIC-UHFFFAOYSA-N

Data: 4 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50412466   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H3 receptor (Homo sapiens (Human))	BDBM50412466 (CHEMBL211486) Show SMILES C(NC1CCCCC1)c1ccc(cc1)-c1ccc(CN2CCCCC2)cc1 Show InChI InChI=1S/C25H34N2/c1-3-7-25(8-4-1)26-19-21-9-13-23(14-10-21)24-15-11-22(12-16-24)20-27-17-5-2-6-18-27/h9-16,25-26H,1-8,17-20H2	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Parma Curated by ChEMBL					Assay Description Displacement of [3H]RAMHA from human histamine H3 receptor expressed in SK-N-MC cells				Bioorg Med Chem 16: 9911-24 (2008) Article DOI: 10.1016/j.bmc.2008.10.029 BindingDB Entry DOI: 10.7270/Q2FQ9XVP
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50412466 (CHEMBL211486) Show SMILES C(NC1CCCCC1)c1ccc(cc1)-c1ccc(CN2CCCCC2)cc1 Show InChI InChI=1S/C25H34N2/c1-3-7-25(8-4-1)26-19-21-9-13-23(14-10-21)24-15-11-22(12-16-24)20-27-17-5-2-6-18-27/h9-16,25-26H,1-8,17-20H2	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Parma Curated by ChEMBL					Assay Description Displacement of [3H]RAMHA from human histamine H3 receptor transfected in SK-N-MC cells				Bioorg Med Chem Lett 16: 4063-7 (2006) Article DOI: 10.1016/j.bmcl.2006.04.092 BindingDB Entry DOI: 10.7270/Q2FX7D7Q
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50412466 (CHEMBL211486) Show SMILES C(NC1CCCCC1)c1ccc(cc1)-c1ccc(CN2CCCCC2)cc1 Show InChI InChI=1S/C25H34N2/c1-3-7-25(8-4-1)26-19-21-9-13-23(14-10-21)24-15-11-22(12-16-24)20-27-17-5-2-6-18-27/h9-16,25-26H,1-8,17-20H2	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	9.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Parma Curated by ChEMBL					Assay Description Displacement of [3H]RAMHA from histamine H3 receptor in rat brain membranes				Bioorg Med Chem Lett 16: 4063-7 (2006) Article DOI: 10.1016/j.bmcl.2006.04.092 BindingDB Entry DOI: 10.7270/Q2FX7D7Q
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50412466 (CHEMBL211486) Show SMILES C(NC1CCCCC1)c1ccc(cc1)-c1ccc(CN2CCCCC2)cc1 Show InChI InChI=1S/C25H34N2/c1-3-7-25(8-4-1)26-19-21-9-13-23(14-10-21)24-15-11-22(12-16-24)20-27-17-5-2-6-18-27/h9-16,25-26H,1-8,17-20H2	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	9.12	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Parma Curated by ChEMBL					Assay Description Displacement of [3H]RAMHA from histamine H3 receptor in Wistar rat brain membrane				Bioorg Med Chem 16: 9911-24 (2008) Article DOI: 10.1016/j.bmc.2008.10.029 BindingDB Entry DOI: 10.7270/Q2FQ9XVP
					More data for this Ligand-Target Pair
Acetylcholinesterase (Rattus norvegicus (rat))	BDBM50412466 (CHEMBL211486) Show SMILES C(NC1CCCCC1)c1ccc(cc1)-c1ccc(CN2CCCCC2)cc1 Show InChI InChI=1S/C25H34N2/c1-3-7-25(8-4-1)26-19-21-9-13-23(14-10-21)24-15-11-22(12-16-24)20-27-17-5-2-6-18-27/h9-16,25-26H,1-8,17-20H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.75E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Parma Curated by ChEMBL					Assay Description Inhibition of acetylcholinesterase in Wistar rat brain homogenate by Ellman's method				Bioorg Med Chem 16: 9911-24 (2008) Article DOI: 10.1016/j.bmc.2008.10.029 BindingDB Entry DOI: 10.7270/Q2FQ9XVP
					More data for this Ligand-Target Pair