BDBM50412475 CHEMBL457005

SMILES: N#Cc1ccc(OCc2ccc(cc2)-c2ccc(CN3CCCCC3)cc2)cc1

InChI Key: InChIKey=NNPWCJUTCAOEPW-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50412475   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50412475 (CHEMBL457005) Show SMILES N#Cc1ccc(OCc2ccc(cc2)-c2ccc(CN3CCCCC3)cc2)cc1 Show InChI InChI=1S/C26H26N2O/c27-18-21-8-14-26(15-9-21)29-20-23-6-12-25(13-7-23)24-10-4-22(5-11-24)19-28-16-2-1-3-17-28/h4-15H,1-3,16-17,19-20H2	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	70.8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Parma Curated by ChEMBL					Assay Description Displacement of [3H]RAMHA from histamine H3 receptor in Wistar rat brain membrane				Bioorg Med Chem 16: 9911-24 (2008) Article DOI: 10.1016/j.bmc.2008.10.029 BindingDB Entry DOI: 10.7270/Q2FQ9XVP
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50412475 (CHEMBL457005) Show SMILES N#Cc1ccc(OCc2ccc(cc2)-c2ccc(CN3CCCCC3)cc2)cc1 Show InChI InChI=1S/C26H26N2O/c27-18-21-8-14-26(15-9-21)29-20-23-6-12-25(13-7-23)24-10-4-22(5-11-24)19-28-16-2-1-3-17-28/h4-15H,1-3,16-17,19-20H2	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	75.9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Parma Curated by ChEMBL					Assay Description Displacement of [3H]RAMHA from human histamine H3 receptor expressed in SK-N-MC cells				Bioorg Med Chem 16: 9911-24 (2008) Article DOI: 10.1016/j.bmc.2008.10.029 BindingDB Entry DOI: 10.7270/Q2FQ9XVP
					More data for this Ligand-Target Pair