BDBM50412476 CHEMBL459542

SMILES: CC1CCN(CCc2ccc(cc2)-c2ccc(CCN3CCC(C)CC3)cc2)CC1

InChI Key: InChIKey=CYSDCSLGWAVYPG-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50412476   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H3 receptor (Homo sapiens (Human))	BDBM50412476 (CHEMBL459542) Show SMILES CC1CCN(CCc2ccc(cc2)-c2ccc(CCN3CCC(C)CC3)cc2)CC1 Show InChI InChI=1S/C28H40N2/c1-23-11-17-29(18-12-23)21-15-25-3-7-27(8-4-25)28-9-5-26(6-10-28)16-22-30-19-13-24(2)14-20-30/h3-10,23-24H,11-22H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	16.6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Parma Curated by ChEMBL					Assay Description Displacement of [3H]RAMHA from human histamine H3 receptor expressed in SK-N-MC cells				Bioorg Med Chem 16: 9911-24 (2008) Article DOI: 10.1016/j.bmc.2008.10.029 BindingDB Entry DOI: 10.7270/Q2FQ9XVP
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50412476 (CHEMBL459542) Show SMILES CC1CCN(CCc2ccc(cc2)-c2ccc(CCN3CCC(C)CC3)cc2)CC1 Show InChI InChI=1S/C28H40N2/c1-23-11-17-29(18-12-23)21-15-25-3-7-27(8-4-25)28-9-5-26(6-10-28)16-22-30-19-13-24(2)14-20-30/h3-10,23-24H,11-22H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	55.0	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Parma Curated by ChEMBL					Assay Description Displacement of [3H]RAMHA from histamine H3 receptor in Wistar rat brain membrane				Bioorg Med Chem 16: 9911-24 (2008) Article DOI: 10.1016/j.bmc.2008.10.029 BindingDB Entry DOI: 10.7270/Q2FQ9XVP
					More data for this Ligand-Target Pair