BDBM50412612 CHEMBL518451

SMILES: CCN(CC(O)(CNC(=O)c1cnn(c1N)-c1ccc(F)cc1)C(F)(F)F)C(=O)c1c(Cl)cc(Cl)cc1Cl

InChI Key: InChIKey=NVQOSFLULKHZHD-UHFFFAOYSA-N

Data: 1 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50412612   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50412612 (CHEMBL518451) Show SMILES CCN(CC(O)(CNC(=O)c1cnn(c1N)-c1ccc(F)cc1)C(F)(F)F)C(=O)c1c(Cl)cc(Cl)cc1Cl Show InChI InChI=1S/C23H20Cl3F4N5O3/c1-2-34(21(37)18-16(25)7-12(24)8-17(18)26)11-22(38,23(28,29)30)10-32-20(36)15-9-33-35(19(15)31)14-5-3-13(27)4-6-14/h3-9,38H,2,10-11,31H2,1H3,(H,32,36)	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.31	n/a	n/a	n/a	n/a	n/a	n/a
Medicines Research Centre Curated by ChEMBL					Assay Description Displacement of fluorescent labelled Dexamethasone from glucocorticoid receptor				Bioorg Med Chem Lett 19: 158-62 (2008) Article DOI: 10.1016/j.bmcl.2008.10.128 BindingDB Entry DOI: 10.7270/Q2XS5V79
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50412612 (CHEMBL518451) Show SMILES CCN(CC(O)(CNC(=O)c1cnn(c1N)-c1ccc(F)cc1)C(F)(F)F)C(=O)c1c(Cl)cc(Cl)cc1Cl Show InChI InChI=1S/C23H20Cl3F4N5O3/c1-2-34(21(37)18-16(25)7-12(24)8-17(18)26)11-22(38,23(28,29)30)10-32-20(36)15-9-33-35(19(15)31)14-5-3-13(27)4-6-14/h3-9,38H,2,10-11,31H2,1H3,(H,32,36)	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	50.1	n/a	n/a	n/a	n/a
Medicines Research Centre Curated by ChEMBL					Assay Description Agonist activity at human glucocorticoid receptor in human A549 cells assessed as transcriptional activity by MMTV luciferase reporter gene assay				Bioorg Med Chem Lett 19: 158-62 (2008) Article DOI: 10.1016/j.bmcl.2008.10.128 BindingDB Entry DOI: 10.7270/Q2XS5V79
					More data for this Ligand-Target Pair