BDBM50412627 CHEMBL445346

SMILES: COc1ccc(Cl)cc1C(=O)Nc1cc(Cl)ccc1O

InChI Key: InChIKey=QFTXEYWITUUVIK-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50412627   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Calcium-activated potassium channel alpha/beta 1 (Homo sapiens (Human))	BDBM50412627 (CHEMBL445346) Show SMILES COc1ccc(Cl)cc1C(=O)Nc1cc(Cl)ccc1O Show InChI InChI=1S/C14H11Cl2NO3/c1-20-13-5-3-8(15)6-10(13)14(19)17-11-7-9(16)2-4-12(11)18/h2-7,18H,1H3,(H,17,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.24	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Activation of BK channel-mediated vasorelaxation activity assessed as reduction in KCl-induced contractile tone				Bioorg Med Chem 17: 319-25 (2008) Article DOI: 10.1016/j.bmc.2008.10.068 BindingDB Entry DOI: 10.7270/Q2P84D59
					More data for this Ligand-Target Pair