BDBM50412628 CHEMBL448335

SMILES: COc1ccc(Cl)cc1C(=O)Nc1cc(C)ccc1O

InChI Key: InChIKey=RPACYQJFRIQCCO-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50412628   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Calcium-activated potassium channel alpha/beta 1 (Homo sapiens (Human))	BDBM50412628 (CHEMBL448335) Show SMILES COc1ccc(Cl)cc1C(=O)Nc1cc(C)ccc1O Show InChI InChI=1S/C15H14ClNO3/c1-9-3-5-13(18)12(7-9)17-15(19)11-8-10(16)4-6-14(11)20-2/h3-8,18H,1-2H3,(H,17,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	27.5	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Activation of BK channel-mediated vasorelaxation activity assessed as reduction in KCl-induced contractile tone				Bioorg Med Chem 17: 319-25 (2008) Article DOI: 10.1016/j.bmc.2008.10.068 BindingDB Entry DOI: 10.7270/Q2P84D59
					More data for this Ligand-Target Pair